| Literature DB >> 29661884 |
Yanyan Zhang1,2, Zhiwei Zheng1,2, Edward Wai-Chi Chan3, Ning Dong2,3, Xiaodong Xia4, Sheng Chen5,3.
Abstract
This study reports the prevalences of qnrVC genes in 74 ciprofloxacin-resistant Vibrio sp. isolates. Two novel functional qnrVC alleles, qnrVC8 and qnrVC9, sharing 98% and 99% nucleotide similarity with qnrVC6 and qnrVC7, respectively, were identified. Our findings suggested that carriage of qnrVC alleles, together with target mutations in gyrA and parC genes, may contribute to the development of fluoroquinolone resistance in Vibrio species, posing a serious threat to public health.Entities:
Keywords: Vibrio; ciprofloxacin resistance; qnrVC
Mesh:
Substances:
Year: 2018 PMID: 29661884 PMCID: PMC6021619 DOI: 10.1128/AAC.00529-18
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191