| Literature DB >> 29660379 |
Seogsong Jeong1, Bo Zheng2, Hongyang Wang3, Qiang Xia4, Lei Chen5.
Abstract
Recent advances have found irregular activities of the nervous system-associated factors in the development and progression of primary liver cancer. These factors contributed in the regulation of migration, proliferation, and apoptosis of cancer cells, and took a role in modulating invasion, metastasis, and recurrence after curative treatment. In clinical researches, neural-related factors were found to be significant prognostic factors, suggesting that the interactions between nervous system and primary liver cancer are indispensable in understanding underlying biological mechanisms. Herein, we reviewed up-to-date achievements in this area and the future perspectives of the interactions between the nervous system and primary liver cancer.Entities:
Keywords: Hepatocellular carcinoma; Intrahepatic cholangiocarcinoma; Nervous system; Neural regulation; Neurotransmitters; Prognostic factors
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Year: 2018 PMID： 29660379 DOI： 10.1016/j.bbcan.2018.04.002
Source DB: PubMed Journal: Biochim Biophys Acta Rev Cancer ISSN： 0304-419X Impact factor: 10.680