Junjie Zeng1, Huaping Liu1, Lizhi Liu2, Weihua Liao1, Ping Hu1, Xiaoyi Wang1, Xuejun Li3, Lunquan Sun4, Youming Zhang1, Xiaoping Yi1. 1. 1 Department of Radiology, Xiangya Hospital, Central South University , Changsha , China. 2. 2 Department of Imaging Diagnosis Center, Sun Yat-sen University Cancer Center , Guangzhou , China. 3. 3 Department of Neurosurgery, Xiangya Hospital, Central South University , Changsha , China. 4. 4 Center for Molecular Medicine,Xiangya Hospital, Central South University , Changsha , China.
Abstract
OBJECTIVES: To analyze the clinicopathological features and the CT and MRI features of patients with paranasal sinus fibrosarcoma. METHODS: Seven patients with surgically and pathologically confirmed paranasal sinus fibrosarcoma were enrolled. Their CT and MRI data and imaging features were retrospectively analyzed in detail. RESULTS: The study participants were two males and five females (median age, 43 years; range, 22-73 years). CT or MRI showed a well-defined (n = 5) or ill-defined (n = 2), irregular (n = 6) or oval (n = 1) mass, with heterogeneous (n = 7) density. The lesions were isointense (n = 4) or hypointense (n = 2) on T1 weighted images, and showed heterogeneous (n = 6) mild hypointensity on T2 weighted images. Expansive (n = 6) and osteolytic (n = 1) bone destruction were observed. The tumors showed marked heterogeneous delayed enhancement (n = 6) on contrast-enhanced MRI images. CONCLUSION: Paranasal sinus fibrosarcomas should be included in the differential diagnosis when a sinonasal neoplasm appears as a well- or ill-defined unilateral large irregular mass with characteristic mild hypointensity on T2 weighted MR images and shows expansive or osteolytic bone destruction and a marked heterogeneous delayed contrast-enhancement pattern.
OBJECTIVES: To analyze the clinicopathological features and the CT and MRI features of patients with paranasal sinus fibrosarcoma. METHODS: Seven patients with surgically and pathologically confirmed paranasal sinus fibrosarcoma were enrolled. Their CT and MRI data and imaging features were retrospectively analyzed in detail. RESULTS: The study participants were two males and five females (median age, 43 years; range, 22-73 years). CT or MRI showed a well-defined (n = 5) or ill-defined (n = 2), irregular (n = 6) or oval (n = 1) mass, with heterogeneous (n = 7) density. The lesions were isointense (n = 4) or hypointense (n = 2) on T1 weighted images, and showed heterogeneous (n = 6) mild hypointensity on T2 weighted images. Expansive (n = 6) and osteolytic (n = 1) bone destruction were observed. The tumors showed marked heterogeneous delayed enhancement (n = 6) on contrast-enhanced MRI images. CONCLUSION: Paranasal sinus fibrosarcomas should be included in the differential diagnosis when a sinonasal neoplasm appears as a well- or ill-defined unilateral large irregular mass with characteristic mild hypointensity on T2 weighted MR images and shows expansive or osteolytic bone destruction and a marked heterogeneous delayed contrast-enhancement pattern.
Authors: Lalit Parida; Israel Fernandez-Pineda; John K Uffman; Andrew M Davidoff; Matthew J Krasin; Alberto Pappo; Bhaskar N Rao Journal: Pediatr Surg Int Date: 2013-05-26 Impact factor: 1.827
Authors: P Pittoni; S Di Lascio; M Conti-Beltraminelli; M C Valli; V Espeli; M Bongiovanni; A Richetti; O Pagani Journal: BMJ Case Rep Date: 2014-06-27