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Literature DB >> 2965877

Increase in levels of serum keratan sulfate following cartilage proteoglycan degradation in the rabbit knee joint.

Abstract

Following injection of chymopapain into a single knee joint in rabbits, serum keratan sulfate levels rose sharply and remained elevated for at least 48 hours before returning to preinjection levels. These changes were accompanied by depletion of proteoglycans from articular cartilage in the injected joint. We conclude that serum keratan sulfate levels rise predictably following acute loss of proteoglycan from a single joint.

Entities: Chemical Disease Species

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Year: 1988 PMID： 2965877 DOI： 10.1002/art.1780310415

Source DB: PubMed Journal: Arthritis Rheum ISSN： 0004-3591

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Cited

12 in total

Review 1. Epidemiology of scleroderma.

Authors: A J Silman
Journal: Ann Rheum Dis Date: 1991-11 Impact factor: 19.103

2. Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in arthritic and normal knees.

Authors: C Belcher; R Yaqub; F Fawthrop; M Bayliss; M Doherty
Journal: Ann Rheum Dis Date: 1997-05 Impact factor: 19.103

3. Effect of longeing and glucosamine supplementation on serum markers of bone and joint metabolism in yearling quarter horses.

Authors: J I Fenton; M W Orth; K A Chlebek-Brown; B D Nielsen; C D Corn; K S Waite; J P Caron
Journal: Can J Vet Res Date: 1999-10 Impact factor: 1.310

Review 4. Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease.

Authors: L S Lohmander
Journal: J Anat Date: 1994-06 Impact factor: 2.610

Review 5. Animal models for osteoarthritis: processes, problems and prospects.

Authors: K P Pritzker
Journal: Ann Rheum Dis Date: 1994-06 Impact factor: 19.103

6. Application of an enzyme-linked immunosorbent-inhibition assay to quantitate the release of KS peptides into fluids of the rat subcutaneous air-pouch model and the effects of chondroprotective drugs on the release process.

Authors: P Kongtawelert; D J Francis; P M Brooks; P Ghosh
Journal: Rheumatol Int Date: 1989 Impact factor: 2.631

Increase in levels of serum keratan sulfate following cartilage proteoglycan degradation in the rabbit knee joint.

Review 1. Epidemiology of scleroderma.

2. Synovial fluid chondroitin and keratan sulphate epitopes, glycosaminoglycans, and hyaluronan in arthritic and normal knees.

3. Effect of longeing and glucosamine supplementation on serum markers of bone and joint metabolism in yearling quarter horses.

Review 4. Articular cartilage and osteoarthrosis. The role of molecular markers to monitor breakdown, repair and disease.

Review 5. Animal models for osteoarthritis: processes, problems and prospects.

6. Application of an enzyme-linked immunosorbent-inhibition assay to quantitate the release of KS peptides into fluids of the rat subcutaneous air-pouch model and the effects of chondroprotective drugs on the release process.

7. Magnetic resonance imaging reflects cartilage proteoglycan degradation in the rabbit knee.

8. Sensitivity of monoclonal antibody, 5-D-4, for the detection of aggrecan, aggrecan fragments, and keratan sulfate.

9. Magnetic resonance imaging of the rabbit knee: detection of cartilage proteoglycan degradation.

10. Systemic sclerosis in Iceland. A nationwide epidemiological study.