| Literature DB >> 29656834 |
Abstract
Tick-borne diseases (TBDs) represent a growing burden for human and animal health worldwide. Several approaches including the use of chemicals with repellency and parasiticidal activity, habitat management, genetic selection of hosts with higher resistance to ticks, and vaccines have been implemented for reducing the risk of TBDs. However, the application of latest gene editing technologies in combination with vaccines likely combining tick and pathogen derived antigens and other control measures should result in the development of effective, safe, and environmentally sound integrated control programs for the prevention and control of TBDs. This paper is not a review of current approaches for the control of ticks and TBDs, but an opinion about future directions in this area.Entities:
Keywords: Autocidal; Genome editing; Microbiota; Omics; Paratransgenesis; Tick; Vaccine
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Year: 2018 PMID: 29656834 DOI: 10.1016/j.ttbdis.2018.04.001
Source DB: PubMed Journal: Ticks Tick Borne Dis ISSN: 1877-959X Impact factor: 3.744