J G Josien Timmerman1, M G H Marit Dekker-van Weering2, M W J M Michel Wouters3, M M Martijn Stuiver4, W Wanda de Kanter5, M M R Miriam Vollenbroek-Hutten6. 1. Roessingh Research and Development, Telemedicine group, Roessinghsbleekweg 33b, 7522 AH Enschede, The Netherlands; Faculty of Electrical Engineering, Mathematics and Computer Science, Telemedicine group, University of Twente, Postbox 217, 7500 AE Enschede, The Netherlands; ZGT Academy, Ziekenhuis Groep Twente, Zilvermeeuw 1, 7609 PP Almelo, The Netherlands. Electronic address: j.timmerman@zgt.nl. 2. Roessingh Research and Development, Telemedicine group, Roessinghsbleekweg 33b, 7522 AH Enschede, The Netherlands. Electronic address: m.dekker@rrd.nl. 3. Department of Surgery, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. Electronic address: m.wouters@nki.nl. 4. Department of Physical Therapy, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands; ACHIEVE, Faculty of Health, Amsterdam University of Applied Sciences, Tafelbergweg 51, 1105 BD Amsterdam, The Netherlands. Electronic address: m.stuiver@nki.nl. 5. Department of Pulmonology, The Netherlands Cancer Institute, Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands. Electronic address: w.dekanter@nki.nl. 6. Faculty of Electrical Engineering, Mathematics and Computer Science, Telemedicine group, University of Twente, Postbox 217, 7500 AE Enschede, The Netherlands; ZGT Academy, Ziekenhuis Groep Twente, Zilvermeeuw 1, 7609 PP Almelo, The Netherlands. Electronic address: m.m.r.hutten@utwente.nl.
Abstract
OBJECTIVES: Our objectives were to 1) characterize daily physical behavior of operable non-small cell lung cancer (NSCLC) patients, from preoperative to six months postoperative using accelerometry, and explore if physical behavior preoperative or one month postoperative is associated with better health outcomes at six months postoperative. METHODS: A prospective study with 23 patients (13 female) diagnosed with primary NSCLC and scheduled for curative lung resection was performed. Outcome measures were assessed two weeks preoperative, and one, three and six months postoperative, and included accelerometer-derived physical behavior measures and the following health outcomes: six minute walking distance (6MWD), questionnaires concerning health-related quality of life (HRQOL), fatigue and distress. RESULTS: On group average, physical behavior showed significant changes over time. Physical behavior worsened following surgery, but improved between one and six months postoperative, almost reaching preoperative levels. However, physical behavior showed high variability between patients in both amount as well as change over time. More time in moderate-to-vigorous physical activity in bouts of 10 min or longer in the first month postoperative was significantly associated with better 6MWD, HRQOL, distress, and fatigue at six months postoperative. CONCLUSION: As expected, curative lung resection impacts physical behavior. Patients who were more active in the first month following surgery reported better health outcome six months postoperative. The large variability in activity patterns over time observed between patients, suggests that physical behavior 'profiling' through detailed monitoring of physical behavior could facilitate tailored goal setting in interventions that target change in physical behavior.
OBJECTIVES: Our objectives were to 1) characterize daily physical behavior of operable non-small cell lung cancer (NSCLC) patients, from preoperative to six months postoperative using accelerometry, and explore if physical behavior preoperative or one month postoperative is associated with better health outcomes at six months postoperative. METHODS: A prospective study with 23 patients (13 female) diagnosed with primary NSCLC and scheduled for curative lung resection was performed. Outcome measures were assessed two weeks preoperative, and one, three and six months postoperative, and included accelerometer-derived physical behavior measures and the following health outcomes: six minute walking distance (6MWD), questionnaires concerning health-related quality of life (HRQOL), fatigue and distress. RESULTS: On group average, physical behavior showed significant changes over time. Physical behavior worsened following surgery, but improved between one and six months postoperative, almost reaching preoperative levels. However, physical behavior showed high variability between patients in both amount as well as change over time. More time in moderate-to-vigorous physical activity in bouts of 10 min or longer in the first month postoperative was significantly associated with better 6MWD, HRQOL, distress, and fatigue at six months postoperative. CONCLUSION: As expected, curative lung resection impacts physical behavior. Patients who were more active in the first month following surgery reported better health outcome six months postoperative. The large variability in activity patterns over time observed between patients, suggests that physical behavior 'profiling' through detailed monitoring of physical behavior could facilitate tailored goal setting in interventions that target change in physical behavior.
Authors: Weijiao Zhou; Katelyn E Webster; Ellen Lavoie Smith; Weiyun Chen; Philip T Veliz; Rishindra M Reddy; Janet L Larson Journal: Support Care Cancer Date: 2022-04-06 Impact factor: 3.603
Authors: Marijke Elizabeth de Leeuwerk; Martine Botjes; Vincent van Vliet; Edwin Geleijn; Vincent de Groot; Erwin van Wegen; Marike van der Schaaf; Jurriaan Tuynman; Chris Dickhoff; Marike van der Leeden Journal: JMIR Cancer Date: 2022-06-24