| Literature DB >> 29656403 |
Sergey A Zhersh1,2, Oleksandr P Blahun1,2, Iryna V Sadkova1, Andrey A Tolmachev1,2, Yurii S Moroz3,4, Pavel K Mykhailiuk1,2.
Abstract
Cyclic saturated aminosulfonyl fluorides were synthesized as their HCl salts. The compounds were found to be stable upon storage and could be used for the protecting-group-free synthesis of sulfonamides. In the presence of the -SO2 F group, the nitrogen atom could be modified by means of acylation, arylation, or reductive amination to give products that have high potential for the synthesis of bioactive compounds.Entities:
Keywords: acylation; amines; nitrogen heterocycles; sulfonamides; sulfur
Year: 2018 PMID： 29656403 DOI： 10.1002/chem.201801140
Source DB: PubMed Journal: Chemistry ISSN： 0947-6539 Impact factor: 5.236