Literature DB >> 2965496

Flare up of joint inflammations induced by cloned helper T cells. Retention of the helper T cells.

I S Klasen1, R M Ladestein, W B van den Berg, R Benner.   

Abstract

Joint inflammations were induced in mice by intra articular (ia) injection of cloned helper T cells specific for methylated bovine serum albumin (mBSA) together with mBSA. Local injection of mBSA several weeks after waning of a joint inflammation induced by cloned helper T cells caused a flare up reaction. This indicates that the helper T cells persisted in the joint after the primary inflammation. In the present paper we show that the helper T cells can also persist for some time in a knee joint in the absence of the specific antigen and/or an inflammatory reaction.

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Year:  1988        PMID： 2965496     DOI： 10.1007/bf01967192

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  10 in total

Review 1.  Functional aspects of helper T cell clones.

Authors:  M H Schreier; R Tees; A A Nordin; R Benner; A T Bianchi; M J van Zwieten
Journal:  Immunobiology       Date:  1982-03       Impact factor: 3.144

2.  Abnormal migration of T lymphocyte clones.

Authors:  M O Dailey; C G Fathman; E C Butcher; E Pillemer; I Weissman
Journal:  J Immunol       Date:  1982-05       Impact factor: 5.422

3.  Antigen handling in antigen-induced arthritis in mice: an autoradiographic and immunofluorescence study using whole joint sections.

Authors:  W B van den Berg; H J van Beusekom; L B van de Putte; W A Zwarts; M van der Sluis
Journal:  Am J Pathol       Date:  1982-07       Impact factor: 4.307

4.  Detection and quantification of experimental joint inflammation in mice by measurement of 99mTc-pertechnetate uptake.

Authors:  M W Kruijsen; W B van den Berg; L B van de Putte; W J van den Broek
Journal:  Agents Actions       Date:  1981-12

5.  Electrical charge of the antigen determines intraarticular antigen handling and chronicity of arthritis in mice.

Authors:  W B van den Berg; L B van de Putte; W A Zwarts; L A Joosten
Journal:  J Clin Invest       Date:  1984-11       Impact factor: 14.808

6.  Exacerbation of antigen-induced arthritis after challenge with intravenous antigen.

Authors:  L B van de Putte; J W Lens; W B van den Berg; M W Kruijsen
Journal:  Immunology       Date:  1983-05       Impact factor: 7.397

7.  Flare-up of delayed-type hypersensitivity initially induced by murine cloned helper T cells.

Authors:  I S Klasen; T H van der Kwast; I G Donselaar; R M Ladestein; R Benner
Journal:  Cell Immunol       Date:  1987-08       Impact factor: 4.868

8.  Joint inflammations and flare-up reactions in mice induced by a helper T cell clone.

Authors:  I S Klasen; I G Donselaar; R M Ladestein; W B van den Berg; R Benner
Journal:  Agents Actions       Date:  1986-12

9.  Flare-up of antigen-induced arthritis in mice after challenge with oral antigen.

Authors:  J W Lens; W B van den Berg; L B van de Putte; L van den Bersselaar
Journal:  Clin Exp Immunol       Date:  1984-11       Impact factor: 4.330

10.  Antigen-induced arthritis in mice. I. Induction of arthritis in various strains of mice.

Authors:  D Brackertz; G F Mitchell; I R Mackay
Journal:  Arthritis Rheum       Date:  1977-04
  10 in total

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