Literature DB >> 29652633

Glucose, insulin, and the carotid body chemoreceptors in humans.

Jacqueline K Limberg1.   

Abstract

Known primarily for its oxygen-sensing capabilities, the carotid body chemoreceptors have recently been implicated, primarily by work in animal models, in the pathophysiology of a number of metabolic conditions. The research presented in this brief review highlights translational work conducted at the Mayo Clinic between 2010 and 2017 in healthy humans and discusses key areas for future work in disease populations.

Entities:  

Keywords:  carotid body; chemoreflex; humans; hypoxic ventilatory response

Mesh:

Substances:

Year:  2018        PMID: 29652633      PMCID: PMC6087880          DOI: 10.1152/physiolgenomics.00032.2018

Source DB:  PubMed          Journal:  Physiol Genomics        ISSN: 1094-8341            Impact factor:   3.107


  52 in total

1.  Hyperoxia blunts counterregulation during hypoglycaemia in humans: possible role for the carotid bodies?

Authors:  Erica A Wehrwein; Rita Basu; Ananda Basu; Timothy B Curry; Robert A Rizza; Michael J Joyner
Journal:  J Physiol       Date:  2010-10-04       Impact factor: 5.182

Review 2.  Denervation of carotid baro- and chemoreceptors in humans.

Authors:  Henri J L M Timmers; Wouter Wieling; John M Karemaker; Jacques W M Lenders
Journal:  J Physiol       Date:  2003-10-03       Impact factor: 5.182

3.  Mechanism of efferent inhibition of carotid body chemoreceptors in the cat.

Authors:  S R Sampson
Journal:  Brain Res       Date:  1972-10-13       Impact factor: 3.252

4.  Species difference in carotid body response of cat and dog to dopamine and serotonin.

Authors:  A M Black; J H Comroe; L Jacobs
Journal:  Am J Physiol       Date:  1972-11

Review 5.  The effects of dopamine on the respiratory system: friend or foe?

Authors:  Agnieszka Ciarka; Jean-Louis Vincent; Philippe van de Borne
Journal:  Pulm Pharmacol Ther       Date:  2006-10-27       Impact factor: 3.410

Review 6.  Insulin resistance: a new consequence of altered carotid body chemoreflex?

Authors:  Silvia V Conde; Maria J Ribeiro; Bernardete F Melo; Maria P Guarino; Joana F Sacramento
Journal:  J Physiol       Date:  2016-06-27       Impact factor: 5.182

7.  Is insulin the new intermittent hypoxia?

Authors:  Jacqueline K Limberg; Timothy B Curry; Nanduri R Prabhakar; Michael J Joyner
Journal:  Med Hypotheses       Date:  2014-03-18       Impact factor: 1.538

8.  Effect of bilateral carotid body resection on the counterregulatory response to hypoglycaemia in humans.

Authors:  Erica A Wehrwein; Jacqueline K Limberg; Jennifer L Taylor; Simmi Dube; Ananda Basu; Rita Basu; Robert A Rizza; Timothy B Curry; Michael J Joyner
Journal:  Exp Physiol       Date:  2015-01       Impact factor: 2.969

Review 9.  Carotid body, insulin, and metabolic diseases: unraveling the links.

Authors:  Sílvia V Conde; Joana F Sacramento; Maria P Guarino; Constancio Gonzalez; Ana Obeso; Lucilia N Diogo; Emilia C Monteiro; Maria J Ribeiro
Journal:  Front Physiol       Date:  2014-10-29       Impact factor: 4.566

10.  Intact blood pressure, but not sympathetic, responsiveness to sympathoexcitatory stimuli in a patient with unilateral carotid body resection.

Authors:  Kathryn F Larson; Jacqueline K Limberg; Sarah E Baker; Michael J Joyner; Timothy B Curry
Journal:  Physiol Rep       Date:  2017-04
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  2 in total

1.  Role of the carotid chemoreceptors in insulin-mediated sympathoexcitation in humans.

Authors:  Jacqueline K Limberg; Blair D Johnson; Michael T Mozer; Walter W Holbein; Timothy B Curry; Nanduri R Prabhakar; Michael J Joyner
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2019-11-20       Impact factor: 3.619

Review 2.  Carotid Body and Metabolic Syndrome: Mechanisms and Potential Therapeutic Targets.

Authors:  Lenise J Kim; Vsevolod Y Polotsky
Journal:  Int J Mol Sci       Date:  2020-07-20       Impact factor: 5.923

  2 in total

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