| Literature DB >> 29650359 |
Abstract
Meiotic drive is an enigmatic process that results from biased segregation of selfish genetic elements that enhance their own transmission and drive evolution. During asymmetric female meiotic divisions, selfish elements segregate preferentially towards the egg rather than polar bodies. Recent findings demonstrate that asymmetric spindle tyrosination helps selfish elements to cheat.Entities:
Keywords: CENP-A; Cdc42; TTL; centromere; meiotic drive; microtubule tyrosination; selfish genetic element; spindle asymmetry
Mesh：
Year: 2018 PMID： 29650359 DOI： 10.1016/j.tcb.2018.03.005
Source DB: PubMed Journal: Trends Cell Biol ISSN： 0962-8924 Impact factor: 20.808