Literature DB >> 29643691

Incidental Meningioma on 68Ga-DOTANOC Positron-Emission Tomography.

Ashwin Singh Parihar1, Rajender Kumar Basher1, Nivedita Rana1, Bhagwant Rai Mittal1.   

Abstract

Entities:  

Year:  2018        PMID: 29643691      PMCID: PMC5883448          DOI: 10.4103/ijnm.IJNM_162_17

Source DB:  PubMed          Journal:  Indian J Nucl Med        ISSN: 0974-0244


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Sir, A 45-year-old woman was being evaluated for suspected recurrence of right adrenocortical carcinoma. She had undergone right mastectomy with adjuvant chemoradiation, 2 years earlier for carcinoma breast. On follow-up, computed tomography (CT) of the abdomen showed an enhancing right suprarenal mass which was revealed as adrenocortical carcinoma after excision. Six-month postsurgery, 68Ga-DOTANOC positron-emission tomography/computed tomography (PET/CT) for suspected disease recurrence showed [Figure 1] a focus of tracer activity in the head (arrow), superior to the physiologic tracer uptake in the pituitary (A, maximum intensity projection image). Corresponding transaxial CT (B) and fused PET/CT (C) images showed a tracer avid (standardized uptake value-max 12.1), dural-based enhancing lesion in the left frontal cortex, diagnosed as meningioma. The patient was asymptomatic and is on follow-up. Meningiomas are slow-growing tumors and express somatostatin receptors. Although the CT characteristics are consistent, the additional avidity on 68Ga-DOTANOC PET imaging adds on to the diagnostic confidence.
Figure 1

68Ga-DOTANOC positron-emission tomography/computed tomography; (a) maximum intensity projection image showing focus of tracer uptake in the head, slightly to the left of midline (arrow); (b) transaxial computed tomography image showing dural-based enhancing lesion in the left frontal cortex (arrow); (c) transaxial fused positron-emission tomography/computed tomography image showing tracer uptake in the dural-based lesion (arrow)

68Ga-DOTANOC positron-emission tomography/computed tomography; (a) maximum intensity projection image showing focus of tracer uptake in the head, slightly to the left of midline (arrow); (b) transaxial computed tomography image showing dural-based enhancing lesion in the left frontal cortex (arrow); (c) transaxial fused positron-emission tomography/computed tomography image showing tracer uptake in the dural-based lesion (arrow)

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Conflicts of interest

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  1 in total

1.  Demonstration of focal physiologic in-vivo somatostatin receptor expression in the caput epididymis of the testes on 68Ga-DOTANOC PET/CT and 177Lu-DOTATATE post-therapy whole body scintigraphy.

Authors:  Ashwin Singh Parihar; Apurva Sood; Ashwani Sood; Ajay Gulati; Bhagwant Rai Mittal
Journal:  Asia Ocean J Nucl Med Biol       Date:  2020
  1 in total

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