Literature DB >> 29641721

Polyhexanide 0.2% in treatment of trophic foot ulcers in leprosy - preliminary study.

Túlio Neutzling Zanchin1, Cássio Battisti Serafini2, Francine Silva Brandão3, José Augusto da Costa Nery3,4.   

Abstract

Leprosy is a chronic infectious disease caused by Mycobacterium leprae, which affects peripheral nerves, skin and mucous membranes. The impairment of neural function as well as sensory or sensory-motor disabilities in leprosy continue to be a problem that requires careful attention in the management of patients with the aim to avoid or minimize their progression to prevent sequelae. One of the most common characteristics of these ulcers is the tendency to chronicity, with variable therapeutic response. In this article, we shall discuss the therapeutic management of thirteen trophic leprosy ulcers in eight patients using polyhexanide 0.2% products.

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Year:  2018        PMID: 29641721      PMCID: PMC5871386          DOI: 10.1590/abd1806-4841.20186655

Source DB:  PubMed          Journal:  An Bras Dermatol        ISSN: 0365-0596            Impact factor:   1.896


  8 in total

Review 1.  Immunology, microbiology, and the recalcitrant wound.

Authors:  P D Thomson
Journal:  Ostomy Wound Manage       Date:  2000-01       Impact factor: 2.629

2.  Management of plantar ulcers in Hansen's disease.

Authors:  V S Chauhan; S S Pandey; V K Shukla
Journal:  Int J Low Extrem Wounds       Date:  2003-09       Impact factor: 2.057

3.  Polihexanide for wound treatment--how it began.

Authors:  B Roth; F H H Brill
Journal:  Skin Pharmacol Physiol       Date:  2010-09-08       Impact factor: 3.479

4.  A practice-oriented recommendation for treatment of critically colonised and locally infected wounds using polihexanide.

Authors:  J Dissemond; V Gerber; A Kramer; G Riepe; R Strohal; A Vasel-Biergans; T Eberlein
Journal:  J Tissue Viability       Date:  2010-08       Impact factor: 2.932

Review 5.  Polyhexanide - safety and efficacy as an antiseptic.

Authors:  Hilde Fjeld; Egil Lingaas
Journal:  Tidsskr Nor Laegeforen       Date:  2016-05-03

Review 6.  Interventions for skin changes caused by nerve damage in leprosy.

Authors:  Liv Merete Reinar; Louise Forsetlund; Arild Bjørndal; Diana Lockwood
Journal:  Cochrane Database Syst Rev       Date:  2008-07-16

Review 7.  [Leprosy in Brazil].

Authors:  Marcelo Grossi Araújo
Journal:  Rev Soc Bras Med Trop       Date:  2003-07-31       Impact factor: 1.581

Review 8.  Antibiotics and antiseptics for pressure ulcers.

Authors:  Gill Norman; Jo C Dumville; Zena E H Moore; Judith Tanner; Janice Christie; Saori Goto
Journal:  Cochrane Database Syst Rev       Date:  2016-04-04
  8 in total

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