Copper Promoted Regio- and Stereoselective Aminochlorination of Alkynes and Alkenes with NFSI.

A simple and rapid copper-promoted aminochlorination of unactivated alkynes and alkenes with N-fluorobenzenesulfonimide (NFSI) was developed. Two series of chloroenamines and chloroamines were obtained in good to high yields. The chlorinated enamines could be obtained in a single E configuration. This reaction involved a radical process and the CuCl2 acted as the Cl source and NFSI as the N source.