| Literature DB >> 2963652 |
Abstract
The effect of W. somnifera on glycosaminoglycan synthesis in the granulation tissue of carrageenin-induced air pouch granuloma was studied. W. somnifera was shown to exert significant inhibitory effect on incorporation of 35S into the granulation tissue. The uncoupling effect on oxidative phosphorylation (ADP/O ratio reduction) was also observed in the mitochondria of granulation tissue. Further, Mg2+ dependent ATPase activity was found to be influenced by W. somnifera. W. somnifera also reduced the succinate dehydrogenase enzyme activity in the mitochondria of granulation tissue.Entities:
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Year: 1987 PMID： 2963652 DOI： 10.1016/0885-4505(87)90091-0
Source DB: PubMed Journal: Biochem Med Metab Biol ISSN： 0885-4505