Literature DB >> 29635779

A retrospective clinico-pathological study comparing lichen planus pigmentosus with ashy dermatosis.

Hui Mei Cheng1, Sai Yee Chuah1, Emily Yiping Gan1, Anjali Jhingan1, Steven Tien Guan Thng1,2.   

Abstract

BACKGROUND/
OBJECTIVES: Controversy persists as to whether lichen planus pigmentosus and ashy dermatosis are separate clinical entities. This study was conducted to examine the clinicopathological features and treatment outcome of the two conditions.
METHODS: A retrospective medical chart review of all patients who were diagnosed with lichen planus pigmentosus or ashy dermatosis was conducted. The information collected included the participants' age at onset, site of onset, duration of disease, presence of precipitating factors, distribution of disease, pigmentation and presence of symptoms. In patients from whom a biopsy was taken the histopathological reports were included.
RESULTS: Altogether 26 patients with ashy dermatosis and 29 with lichen planus pigmentosus were included in the study. Compared with ashy dermatosis, lichen planus pigmentosus had a more localised distribution with a preponderance for facial involvement, compared with the truncal preponderance in ashy dermatosis. Ashy dermatosis tended to have a more stable clinical course than lichen planus pigmentosus, which was more likely to wax and wane. The utility of histopathology in differentiating between the two conditions is low.
CONCLUSION: Ashy dermatosis and lichen planus pigmentosus, as defined in this study, appear to be two separate clinical entities with distinguishable clinical features and natural histories.
© 2018 The Australasian College of Dermatologists.

Entities:  

Keywords:  ashy dermatosis; erythema dyschromicum perstans; idiopathic eruptive macular pigmentation; lichen planus pigmentosus; pigmentary disorder

Mesh:

Year:  2018        PMID: 29635779     DOI: 10.1111/ajd.12813

Source DB:  PubMed          Journal:  Australas J Dermatol        ISSN: 0004-8380            Impact factor:   2.875


  3 in total

Review 1.  Erythema dyschromicum perstans: A case report and systematic review of histologic presentation and treatment.

Authors:  N Leung; M Oliveira; M A Selim; L McKinley-Grant; E Lesesky
Journal:  Int J Womens Dermatol       Date:  2018-09-27

2.  Ashy Dermatosis and Lichen Planus Pigmentosus: The Histopathological Differences.

Authors:  Suthinee Rutnin; Siriorn Udompanich; Nathathai Pratumchart; Sarawin Harnchoowong; Vasanop Vachiramon
Journal:  Biomed Res Int       Date:  2019-10-28       Impact factor: 3.411

3.  Combination therapy with prednisone and isotretinoin in early erythema dyschromicum perstans: A retrospective series.

Authors:  Aisleen Diaz; Ryan Gillihan; Kiran Motaparthi; Adam Rees
Journal:  JAAD Case Rep       Date:  2020-02-19
  3 in total

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