Literature DB >> 29633150

Genetics of personalized medicine: cancer and rare diseases.

Inês Teles Siefers Alves1, Manuel Condinho2,3, Sónia Custódio4, Bruna F Pereira2,3, Rafael Fernandes2,3, Vânia Gonçalves2,3, Paulo J da Costa2,3, Rafaela Lacerda2,3, Ana Rita Marques2,3, Patrícia Martins-Dias2,3, Gonçalo R Nogueira2,3, Ana Rita Neves2,3, Patrícia Pinho5, Raquel Rodrigues4, Eva Rolo4, Joana Silva2,3, André Travessa4, Rosário Pinto Leite5, Ana Sousa4, Luísa Romão2,3.   

Abstract

The 21st annual meeting of the Portuguese Society of Human Genetics (SPGH), organized by Luísa Romão, Ana Sousa and Rosário Pinto Leite, was held in Caparica, Portugal, from the 16th to the 18th of November 2017. Having entered an era in which personalized medicine is emerging as a paradigm for disease diagnosis, treatment and prevention, the program of this meeting intended to include lectures by leading national and international scientists presenting exceptional findings on the genetics of personalized medicine. Various topics were discussed, including cancer genetics, transcriptome dynamics and novel therapeutics for cancers and rare disorders that are designed to specifically target molecular alterations in individual patients. Several panel discussions were held to emphasize (ethical) issues associated with personalized medicine, including genetic cancer counseling.

Entities:  

Keywords:  Cancer genetics; Genome architecture; Human genetics; Personalized medicine; Rare disorders

Mesh：

Year:  2018        PMID： 29633150     DOI： 10.1007/s13402-018-0379-3

Source DB:  PubMed          Journal:  Cell Oncol (Dordr)        ISSN： 2211-3428            Impact factor:   6.730


  42 in total

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Authors:  Tom Maniatis; Bosiljka Tasic
Journal:  Nature       Date:  2002-07-11       Impact factor: 49.962

2.  The path to personalized medicine.

Authors:  Margaret A Hamburg; Francis S Collins
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3.  Family history and women with ovarian cancer: is it asked and does it matter?: An observational study.

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Journal:  Int J Gynecol Cancer       Date:  2012-02       Impact factor: 3.437

4.  Communicating risk under conditions of uncertainty: not as simple as it may seem.

Authors:  Marlyse F Haward; John M Lorenz
Journal:  Acta Paediatr       Date:  2011-03-17       Impact factor: 2.299

Review 5.  The role of alternative splicing coupled to nonsense-mediated mRNA decay in human disease.

Authors:  Paulo J da Costa; Juliane Menezes; Luísa Romão
Journal:  Int J Biochem Cell Biol       Date:  2017-07-22       Impact factor: 5.085

Review 6.  Lung cancer-associated brain metastasis: Molecular mechanisms and therapeutic options.

Authors:  Meysam Yousefi; Tayyeb Bahrami; Arash Salmaninejad; Rahim Nosrati; Parisa Ghaffari; Seyed H Ghaffari
Journal:  Cell Oncol (Dordr)       Date:  2017-09-18       Impact factor: 6.730

7.  UNR/CSDE1 Drives a Post-transcriptional Program to Promote Melanoma Invasion and Metastasis.

Authors:  Laurence Wurth; Panagiotis Papasaikas; David Olmeda; Nadine Bley; Guadalupe T Calvo; Santiago Guerrero; Daniela Cerezo-Wallis; Javier Martinez-Useros; María García-Fernández; Stefan Hüttelmaier; Maria S Soengas; Fátima Gebauer
Journal:  Cancer Cell       Date:  2016-10-27       Impact factor: 31.743

8.  Tumor suppressor properties of the splicing regulatory factor RBM10.

Authors:  Jordi Hernández; Elias Bechara; Doerte Schlesinger; Javier Delgado; Luis Serrano; Juan Valcárcel
Journal:  RNA Biol       Date:  2016       Impact factor: 4.652

9.  Mapping the hallmarks of lung adenocarcinoma with massively parallel sequencing.

Authors:  Marcin Imielinski; Alice H Berger; Peter S Hammerman; Bryan Hernandez; Trevor J Pugh; Eran Hodis; Jeonghee Cho; James Suh; Marzia Capelletti; Andrey Sivachenko; Carrie Sougnez; Daniel Auclair; Michael S Lawrence; Petar Stojanov; Kristian Cibulskis; Kyusam Choi; Luc de Waal; Tanaz Sharifnia; Angela Brooks; Heidi Greulich; Shantanu Banerji; Thomas Zander; Danila Seidel; Frauke Leenders; Sascha Ansén; Corinna Ludwig; Walburga Engel-Riedel; Erich Stoelben; Jürgen Wolf; Chandra Goparju; Kristin Thompson; Wendy Winckler; David Kwiatkowski; Bruce E Johnson; Pasi A Jänne; Vincent A Miller; William Pao; William D Travis; Harvey I Pass; Stacey B Gabriel; Eric S Lander; Roman K Thomas; Levi A Garraway; Gad Getz; Matthew Meyerson
Journal:  Cell       Date:  2012-09-14       Impact factor: 41.582

Review 10.  The genetic heterogeneity of colorectal cancer predisposition - guidelines for gene discovery.

Authors:  M M Hahn; R M de Voer; N Hoogerbrugge; M J L Ligtenberg; R P Kuiper; A Geurts van Kessel
Journal:  Cell Oncol (Dordr)       Date:  2016-06-09       Impact factor: 6.730
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  1 in total

1.  A multiplexed circulating tumor DNA detection platform engineered from 3D-coded interlocked DNA rings.

Authors:  Sha Yang; Xinyu Zhan; Xiaoqi Tang; Shuang Zhao; Lianyu Yu; Mingxuan Gao; Dan Luo; Yunxia Wang; Kai Chang; Ming Chen
Journal:  Bioact Mater       Date:  2021-09-11
  1 in total

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