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Literature DB >> 29632182

Profile of Alexander Y. Rudensky, winner of the 2018 Vilcek Prize in Biomedical Science.

Prashant Nair¹, Jan Vilcek².

Abstract

Mesh：

Year: 2018 PMID： 29632182 PMCID： PMC5924943 DOI： 10.1073/pnas.1804659115

Source DB: PubMed Journal: Proc Natl Acad Sci U S A ISSN： 0027-8424 Impact factor: 11.205

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References

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13 in total

1. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

Authors: M Itoh; T Takahashi; N Sakaguchi; Y Kuniyasu; J Shimizu; F Otsuka; S Sakaguchi
Journal: J Immunol Date: 1999-05-01 Impact factor: 5.422

2. Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336.

Authors: Jason D Fontenot; Marc A Gavin; Alexander Y Rudensky
Journal: J Immunol Date: 2017-02-01 Impact factor: 5.422

3. Immunoglobulin-specific T-B cell interaction. II. T cell clones recognize the processed form of B cells' own surface immunoglobulin in the context of the major histocompatibility complex class II molecule.

Authors: V L Yurin; A Y Rudensky; S M Mazel; J M Blechman
Journal: Eur J Immunol Date: 1989-09 Impact factor: 5.532

4. A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndrome.

Authors: C L Bennett; M E Brunkow; F Ramsdell; K C O'Briant; Q Zhu; R L Fuleihan; A O Shigeoka; H D Ochs; P F Chance
Journal: Immunogenetics Date: 2001-08 Impact factor: 2.846

5. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

Authors: M E Brunkow; E W Jeffery; K A Hjerrild; B Paeper; L B Clark; S A Yasayko; J E Wilkinson; D Galas; S F Ziegler; F Ramsdell
Journal: Nat Genet Date: 2001-01 Impact factor: 38.330

Profile of Alexander Y. Rudensky, winner of the 2018 Vilcek Prize in Biomedical Science.

1. Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance.

2. Pillars Article: Foxp3 Programs the Development and Function of CD4+CD25+ Regulatory T Cells. Nat. Immunol. 2003. 4: 330-336.

3. Immunoglobulin-specific T-B cell interaction. II. T cell clones recognize the processed form of B cells' own surface immunoglobulin in the context of the major histocompatibility complex class II molecule.

4. A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndrome.

5. Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse.

6. Immunoglobulin-specific T-B cell interaction. I. Presentation of self immunoglobulin determinants by B lymphocytes.

7. Foxp3 programs the development and function of CD4+CD25+ regulatory T cells.

8. Transient regulatory T cell ablation deters oncogene-driven breast cancer and enhances radiotherapy.

9. A Distinct Function of Regulatory T Cells in Tissue Protection.

10. Metabolites produced by commensal bacteria promote peripheral regulatory T-cell generation.