Literature DB >> 29627800

Cystic fibrosis pathogens survive for extended periods within cough-generated droplet nuclei.

Michelle E Wood1,2,3, Rebecca E Stockwell1,3, Graham R Johnson4, Kay A Ramsay1,3, Laura J Sherrard1,5, Timothy J Kidd1,6,7, Joyce Cheney8, Emma L Ballard9, Peter O'Rourke9, Nassib Jabbour4, Claire E Wainwright3,7,8, Luke D Knibbs10, Peter D Sly3,7, Lidia Morawska4, Scott C Bell1,2,3.   

Abstract

The airborne route is a potential pathway in the person-to-person transmission of bacterial strains among cystic fibrosis (CF) populations. In this cross-sectional study, we investigate the physical properties and survival of common non-Pseudomonas aeruginosa CF pathogens generated during coughing. We conclude that Gram-negative bacteria and Staphylococcus aureus are aerosolised during coughing, can travel up to 4 m and remain viable within droplet nuclei for up to 45 min. These results suggest that airborne person-to-person transmission is plausible for the CF pathogens we measured. © Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Entities:  

Keywords:  cystic fibrosis; infection control

Mesh:

Substances:

Year:  2018        PMID: 29627800     DOI: 10.1136/thoraxjnl-2018-211567

Source DB:  PubMed          Journal:  Thorax        ISSN: 0040-6376            Impact factor:   9.139


  5 in total

1.  The Impact of Hospital-Ward Ventilation on Airborne-Pathogen Exposure.

Authors:  Nicola Mingotti; Dorothy Grogono; Gennaro Dello Ioio; Martin Curran; Kathryn Barbour; Marlene Taveira; Josie Rudman; Charles S Haworth; R Andres Floto; Andrew W Woods
Journal:  Am J Respir Crit Care Med       Date:  2021-03-15       Impact factor: 21.405

2.  Duplex real-time PCR assay for the simultaneous detection of Achromobacter xylosoxidans and Achromobacter spp.

Authors:  Erin P Price; Valentina Soler Arango; Timothy J Kidd; Tamieka A Fraser; Thuy-Khanh Nguyen; Scott C Bell; Derek S Sarovich
Journal:  Microb Genom       Date:  2020-07-15

3.  Quantitative real-time PCR assay for the rapid identification of the intrinsically multidrug-resistant bacterial pathogen Stenotrophomonas maltophilia.

Authors:  Tamieka A Fraser; Mikaela G Bell; Patrick N A Harris; Scott C Bell; Haakon Bergh; Thuy-Khanh Nguyen; Timothy J Kidd; Graeme R Nimmo; Derek S Sarovich; Erin P Price
Journal:  Microb Genom       Date:  2019-10-16

4.  Environmental Microbial Contamination during Cystic Fibrosis Group-Based Psychotherapy.

Authors:  Martina Rossitto; Paola Tabarini; Vanessa Tuccio Guarna Assanti; Enza Montemitro; Arianna Pompilio; Ersilia Vita Fiscarelli
Journal:  Int J Environ Res Public Health       Date:  2021-01-28       Impact factor: 3.390

5.  In situ measurements of human cough aerosol hygroscopicity.

Authors:  Robert Groth; Luke T Cravigan; Sadegh Niazi; Zoran Ristovski; Graham R Johnson
Journal:  J R Soc Interface       Date:  2021-05-05       Impact factor: 4.118

  5 in total

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