Literature DB >> 2962672

Gas chromatographic/mass spectrometric studies of the urinary metabolites of male rats given indan.

K O Yu1, C T Olson, M J Ferry, M P Serve.   

Abstract

The identified urinary metabolites of male rats exposed to indan are: 1- and 2-indanone; 1-, 2- and 5-indanol; 2- and 3-hydroxyl-1-indanone; and cis- and trans-indan-1,2-diol. Indan causes kidney damage in male rats in a manner similar to the cyclic hydrocarbons cis- and trans-decalin and JP-10. Lesions produced by indan occur only in male rats and not in female or control rats.

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Year:  1987        PMID: 2962672     DOI: 10.1002/bms.1200141114

Source DB:  PubMed          Journal:  Biomed Environ Mass Spectrom        ISSN: 0887-6134


  1 in total

1.  Regiospecific and stereoselective hydroxylation of 1-indanone and 2-indanone by naphthalene dioxygenase and toluene dioxygenase.

Authors:  S M Resnick; D S Torok; K Lee; J M Brand; D T Gibson
Journal:  Appl Environ Microbiol       Date:  1994-09       Impact factor: 4.792

  1 in total

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