| Literature DB >> 29626570 |
Omar M Aboumarzouk1, Patrick Jones2, Tarik Amer3, Dimitris Kotsiris4, Esteban Emiliani4, Bhaskar Somani4, Panagiotis Kallidonis4, Thomas Tailly4, Gohkan Atis4, Francesco Greco4, Stephan Hruby4, Mario Alvarez4, Khalid Al-Rumaihi5, Ahmad Shamsodini5, Abdulla Al-Ansari4, Ahmed Shokeir6.
Abstract
Use of α-blockers for medical expulsive therapy (MET) has been the subject of huge debate in urology. Moreover, there have been a number of randomized controlled trials with differing results. We conducted a systematic review and meta-analysis of randomized controlled trials investigating the efficacy of α-blockers for MET. This review confirms there is a role for α-blockers in MET for ureteric stones specifically in stones >5 mm and distal ureteric stones, which is associated with improved stone expulsion. However, there is a slight increase in risk of nonsignificant side effects.Entities:
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Year: 2018 PMID： 29626570 DOI： 10.1016/j.urology.2018.03.028
Source DB: PubMed Journal: Urology ISSN： 0090-4295 Impact factor: 2.649