Literature DB >> 29626027

Lesson of the month 1: Massive spontaneous haematomas in an elderly man.

Francesco Fiorini1, Louise Braddick2, Hasnain Hashim3, Robert M Ayto3, Alana Jacobs3, Yetunde Baoku3, Shahir S Hamdulay4.   

Abstract

A 73-year-old man presented with bilateral leg pain and swelling, and no history of trauma or bleeding disorders. Clinical examination, biochemistry and magnetic resonance imaging of the thighs were suggestive of muscle haematomas. These progressed significantly during the admission, requiring blood transfusion. Normal vascular anatomy on computed tomography, renal and liver function, and absence of infection made a bleeding diathesis more likely. This may be caused by coagulation defects, platelet disorders and vascular fragility. An undetectable serum ascorbic acid level confirmed the clinical suspicion of scurvy, and administration of vitamin C resulted in rapid improvement. Our case provides a structured approach to the diagnosis of bleeding disorders and scurvy, a treatable and potentially fatal disease which is often forgotten. © Royal College of Physicians 2018. All rights reserved.

Entities:  

Keywords:  Muscle haematomas; bleeding disorders; scurvy

Mesh:

Substances:

Year:  2018        PMID: 29626027      PMCID: PMC6303442          DOI: 10.7861/clinmedicine.18-2-180

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  2 in total

Review 1.  Scurvy: a disease almost forgotten.

Authors:  Jesse M Olmedo; James A Yiannias; Elizabeth B Windgassen; Michael K Gornet
Journal:  Int J Dermatol       Date:  2006-08       Impact factor: 2.736

Review 2.  Adult scurvy.

Authors:  J V Hirschmann; G J Raugi
Journal:  J Am Acad Dermatol       Date:  1999-12       Impact factor: 11.527

  2 in total

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