Literature DB >> 29624246

SIMULTANEOUS ASSAY OF ARIPIPRAZOLE AND ITS ACTIVE METABOLITE IN SERUM BY HPLC.

Dorota Marszalek, Anna Goldnik, Tomasz Pawinski, Grzegorz Malek, Aleksander Somogi, Anna Mach.   

Abstract

A rapid, convenient, precise HPLC method was developed for the simultaneous determination of aripiprazole and its active metabolite dehydroaripiprazole in blood serum. The separation was carried out by RP HPLC on Symmetry C₁₈ column (150 x 4.6 mm; 5 μm). The mobile phase was composed of acetonitrile: water (30 : 70, v/v), pH 3.0 adjusted with o-phosphoric acid. The detection was monitored at 220 nm.

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Year:  2017        PMID: 29624246

Source DB:  PubMed          Journal:  Acta Pol Pharm        ISSN: 0001-6837            Impact factor:   0.330


  1 in total

1.  Effect Of Chinese Herb Danzhi Xiaoyao Pills On Pharmacokinetics Of Venlafaxine In Beagles.

Authors:  Yong-Liang Zhu; Shuang-Long Li; Ke-Li Chen; Kun-Peng Ma; De-Qian Wu; Xiang-Jun Qiu
Journal:  Drug Des Devel Ther       Date:  2019-09-20       Impact factor: 4.162

  1 in total

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