Literature DB >> 29624070

Fluoroalkylsulfonyl Chlorides Promoted Vicinal Chloro-fluoroalkylthiolation of Alkenes and Alkynes.

Lvqi Jiang1, Tianqi Ding1, Wen-Bin Yi1, Xin Zeng1, Wei Zhang2.   

Abstract

The unprecedented use of CF3SO2Cl for direct bifunctional chloro-trifluoromethylthiolation of alkenes and alkynes is reported. CF3SCl, which is generated by the reduction of PPh3, undergoes electrophilic addition and then chlorination to give the bifunctionalized products without using an additional chlorine source. The method is also applicable for chloro-difluoromethylthiolation using CF2HSO2Cl.

Entities:  

Year:  2018        PMID： 29624070     DOI： 10.1021/acs.orglett.8b00581

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

1.  Organophosphorus-Catalyzed Deoxygenation of Sulfonyl Chlorides: Electrophilic (Fluoroalkyl)sulfenylation by PIII /PV =O Redox Cycling.

Authors:  Avipsa Ghosh; Morgan Lecomte; Shin-Ho Kim-Lee; Alexander T Radosevich
Journal:  Angew Chem Int Ed Engl       Date:  2019-01-25       Impact factor: 15.336

2.  Metal-free visible-light-enabled vicinal trifluoromethyl dithiolation of unactivated alkenes.

Authors:  Xiaojuan Li; Qiang Zhang; Weigang Zhang; Jinzhu Ma; Yi Wang; Yi Pan
Journal:  Beilstein J Org Chem       Date:  2021-02-24       Impact factor: 2.883

Review 3.  Sulforaphane and Its Bifunctional Analogs: Synthesis and Biological Activity.

Authors:  Łukasz Janczewski
Journal:  Molecules       Date:  2022-03-07       Impact factor: 4.411

Review 4.  Recent advances in intermolecular 1,2-difunctionalization of alkenes involving trifluoromethylthiolation.

Authors:  Li Yan-Mei; Fu Jin-Feng; He Long-Qiang; Li Wei-Na; Esmail Vessally
Journal:  RSC Adv       Date:  2021-07-13       Impact factor: 4.036
  4 in total

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