| Literature DB >> 29623408 |
Gabriele Röhrig1, Gerald Kolb2.
Abstract
Anticoagulation in geriatric patients is challenging regarding the risk of bleeding complications and thromboembolic problems. Age, comorbidities, such as renal insufficiency and polymedication have a vital impact on bleeding and thromboembolic risks; however, age is not an exclusion criterion for withholding anticoagulation. Age is the main risk factor for deep vein thrombosis and atrial fibrillation becomes more relevant with aging. Older patients with atrial fibrillation have a particularly high risk of having a stroke. Therefore, very old patients benefit particularly from oral anticoagulation because the risk of bleeding is outweighed by the clinical benefit of stroke prevention. Risk of bleeding and thromboembolic problems can be easily assessed by established diagnostic tools. This article reviews the epidemiology of thromboembolic problems in the aged as well as current diagnostic and therapeutic steps for primary and secondary prevention.Entities:
Keywords: Anticoagulants; Atrial fibrillation; Bleeding; Deep-vein thrombosis; Embolisms
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Year: 2018 PMID: 29623408 DOI: 10.1007/s00391-018-1384-x
Source DB: PubMed Journal: Z Gerontol Geriatr ISSN: 0948-6704 Impact factor: 1.281