Literature DB >> 29623187

Moxifloxacin-induced tinnitus in an older adult.

Amber Onoh1, Sunny A Linnebur1, Danielle R Fixen2.   

Abstract

An increased risk of bacterial resistance toward fluoroquinolones and the increased risk of disabling and serious adverse effects prompted the US Food and Drug Administration to recommend limiting fluoroquinolone use to the treatment of community-acquired pneumonia, skin and skin-structure infections, bacterial sinusitis, plague, chronic bronchitis exacerbations, and complicated intra-abdominal infections. We report a case of moxifloxacin-induced tinnitus in an older adult prescribed oral moxifloxacin 400 mg for 5 days for the treatment of acute diverticulitis, due to allergies to nonfluoroquinolone preferred agents. A thorough literature review provided few other reported incidents of this rare and serious adverse event.

Entities:  

Keywords:  adverse drug reaction; fluoroquinolone; moxifloxacin; tinnitus

Year:  2018        PMID: 29623187      PMCID: PMC5881981          DOI: 10.1177/2042098618754483

Source DB:  PubMed          Journal:  Ther Adv Drug Saf        ISSN: 2042-0986


  8 in total

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Journal:  Ther Drug Monit       Date:  2009-02       Impact factor: 3.681

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Journal:  Drug Saf       Date:  1993-08       Impact factor: 5.606

6.  Diagnosis and management of complicated intra-abdominal infection in adults and children: guidelines by the Surgical Infection Society and the Infectious Diseases Society of America.

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Review 7.  Effects of NSAIDs on the Inner Ear: Possible Involvement in Cochlear Protection.

Authors:  Tomofumi Hoshino; Keiji Tabuchi; Akira Hara
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8.  Review of salicylate-induced hearing loss, neurotoxicity, tinnitus and neuropathophysiology.

Authors:  A Sheppard; S H Hayes; G-D Chen; M Ralli; R Salvi
Journal:  Acta Otorhinolaryngol Ital       Date:  2014-04       Impact factor: 2.124

  8 in total

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