| Literature DB >> 2962287 |
T A Ryan1, J Myers, D Holowka, B Baird, W W Webb.
Abstract
Strong steric interactions among proteins on crowded living cell surfaces were revealed by measurements of the equilibrium spatial distributions of proteins in applied potential gradients. The fraction of accessible surface occupied by mobile surface proteins can be accurately represented by including steric exclusion in the statistical thermodynamic analysis of the data. The analyses revealed enhanced, concentration-dependent activity coefficients, implying unanticipated thermodynamic activity even at typical cell surface receptor concentrations.Mesh：
Substances：
Year: 1988 PMID： 2962287 DOI： 10.1126/science.2962287
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728