Literature DB >> 29622826

Hot Tub Lung: An Intriguing Diffuse Parenchymal Lung Disease.

Mohan Rudrappa1,2, Laxmi Kokatnur2.   

Abstract

In pulmonary medicine, identical pathogenesis due to varied etiological agents can present with indistinguishable clinical presentation, and produce similar laboratory and radiological changes. The importance of eliciting detailed occupational and social history from patients cannot be stressed enough when dealing with patients suffering from diffuse parenchymal lung diseases. Hot Tub Lung(HTL) is a perplexing pulmonary disease attributed to the Mycobacterium Avium-intracellulare Complex (MAC). MAC is a ubiquitous atypical mycobacterium present in moist environment, and is not considered pathogenic, without the predisposing conditions like immunosuppression. However, HTL is a unique disease seen in healthy individuals following the exposure to contaminated hot water in spas. The less virulent MAC will, in healthy individual will elicit mild granulomatous inflammation particularly around the peribronchiolar region, which leads to the development of diffuse parenchymal lung. We report a case of HTL to increase the awareness of this rare and enigmatic disease among medical professionals, and to reiterate the importance of eliciting social and occupational details in clinical practice.

Entities:  

Keywords:  Atypical Mycobacterium; Hot Tube Lung; Hypersensitivity Pneumonitis; Mycobacterium Avium-intracellulare Complex (MAC)

Mesh:

Substances:

Year:  2017        PMID: 29622826      PMCID: PMC5870233          DOI: 10.4314/gmj.v51i3.8

Source DB:  PubMed          Journal:  Ghana Med J        ISSN: 0016-9560


  18 in total

1.  Mycobacterial hypersensitivity pneumonitis requires TLR9-MyD88 in lung CD11b+ CD11c+ cells.

Authors:  H Daito; T Kikuchi; T Sakakibara; K Gomi; T Damayanti; J Zaini; N Tode; M Kanehira; S Koyama; S Fujimura; M Ebina; K J Ishii; S Akira; T Takai; A Watanabe; T Nukiwa
Journal:  Eur Respir J       Date:  2011-01-27       Impact factor: 16.671

2.  Hot-tub lung: hypersensitivity to Mycobacterium avium but not hypersensitivity pneumonitis.

Authors:  Ritesh Agarwal; Alok Nath
Journal:  Respir Med       Date:  2006-05-15       Impact factor: 3.415

3.  Nontuberculous mycobacteria in aerosol droplets and bulk water samples from therapy pools and hot tubs.

Authors:  Craig S Glazer; John W Martyny; Ben Lee; Tracy L Sanchez; Tricia M Sells; Lee S Newman; James Murphy; Leonid Heifets; Cecile S Rose
Journal:  J Occup Environ Hyg       Date:  2007-11       Impact factor: 2.155

4.  Hot tub lung: an occupational hazard.

Authors:  Harald Fjällbrant; Magnus Akerstrom; Erik Svensson; Eva Andersson
Journal:  Eur Respir Rev       Date:  2013-03-01

5.  Molecular identification of potential pathogens in water and air of a hospital therapy pool.

Authors:  Largus T Angenent; Scott T Kelley; Allison St Amand; Norman R Pace; Mark T Hernandez
Journal:  Proc Natl Acad Sci U S A       Date:  2005-03-15       Impact factor: 11.205

6.  Hypersensitivity pneumonitis caused by Mycobacterium avium subsp. hominissuis in a hot tub, as proven by IS1245 RFLP and rep-PCR typing.

Authors:  Rianne J C van der Zanden; Cecile Magis-Escurra; Wiel C M de Lange; Wouter Hoefsloot; Martin J Boeree; Jakko van Ingen; Dick van Soolingen
Journal:  Int J Mycobacteriol       Date:  2012-08-24

Review 7.  Hypersensitivity pneumonitis reaction to Mycobacterium avium in household water.

Authors:  Theodore K Marras; Richard J Wallace; Laura L Koth; Michael S Stulbarg; Clayton T Cowl; Charles L Daley
Journal:  Chest       Date:  2005-02       Impact factor: 9.410

8.  Hot tub lung mimicking classic acute and chronic hypersensitivity pneumonitis: two case reports.

Authors:  Geetika Verma; Frances Jamieson; Pamela Chedore; David Hwang; Scott Boerner; William R Geddie; Kenneth R Chapman; Theodore K Marras
Journal:  Can Respir J       Date:  2007-09       Impact factor: 2.409

Review 9.  Surrounded by mycobacteria: nontuberculous mycobacteria in the human environment.

Authors:  J O Falkinham
Journal:  J Appl Microbiol       Date:  2009-02-18       Impact factor: 3.772

10.  Epidemiology of infection by nontuberculous Mycobacteria. III. Isolation of potentially pathogenic mycobacteria from aerosols.

Authors:  S L Wendt; K L George; B C Parker; H Gruft; J O Falkinham
Journal:  Am Rev Respir Dis       Date:  1980-08
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