Literature DB >> 29622284

In vitro combination of voriconazole with micafungin against azole-resistant clinical isolates of Aspergillus fumigatus from different geographical regions.

Hamed Fakhim1, Afsane Vaezi2, Eric Dannaoui3, Cheshta Sharma4, Bita Mousavi5, Anuradha Chowdhary6, Jacques F Meis7, Hamid Badali8.   

Abstract

In vitro interaction of voriconazole with micafungin was evaluated against 33 clinical Aspergillus fumigatus isolates, including azole-resistant (n=31) and -susceptible (n=2) isolates. Interaction was synergistic for only 1 resistant isolate carrying the TR34/L98H mutation. No antagonistic effects were observed for 96.8% of azole-resistant isolates.
Copyright © 2018 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Aspergillus fumigatus; In vitro interactions; Micafungin; Voriconazole

Mesh：

Substances：

Year:  2018        PMID： 29622284     DOI： 10.1016/j.diagmicrobio.2018.03.003

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  4 in total

1.  Low In Vitro Antifungal Activity of Tavaborole against Yeasts and Molds from Onychomycosis.

Authors:  Mahdi Abastabar; Iman Haghani; Tahereh Shokohi; Mohammad Taghi Hedayati; Seyed Reza Aghili; Ali Jedi; Sulmaz Dadashi; Shafigheh Shabanzadeh; Tahereh Hosseini; Narges Aslani; Jacques F Meis; Hamid Badali
Journal:  Antimicrob Agents Chemother       Date:  2018-11-26       Impact factor: 5.191

2.  Synergistic effects of vorinostat (SAHA) and azoles against Aspergillus species and their biofilms.

Authors:  Bo Tu; Gendi Yin; Hui Li
Journal:  BMC Microbiol       Date:  2020-02-07       Impact factor: 3.605

Review 3.  Augmenting Azoles with Drug Synergy to Expand the Antifungal Toolbox.

Authors:  Aidan Kane; Dee A Carter
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-14

4.  In vitro interaction of isavuconazole and anidulafungin against azole-susceptible and azole-resistant Aspergillus fumigatus isolates.

Authors:  J B Buil; R J M Brüggemann; L Bedin Denardi; W J G Melchers; P E Verweij
Journal:  J Antimicrob Chemother       Date:  2020-09-01       Impact factor: 5.790
  4 in total

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