Electrochemical synthesis of nitrogen-doped carbon quantum dots decorated copper oxide for the sensitive and selective detection of non-steroidal anti-inflammatory drug in berries.

We report a sensitive non-steroidal anti-inflammatory drug aspirin (ASA) sensor studies using the nitrogen-doped carbon quantum dots (N-CQD) decorated copper oxide (Cu2O). A simplistic approach of electrochemical deposition method has been used to prepare the N-CQD incorporated with copper oxide (N-CQD/Cu2O) and the resulting composite has characterized by analytical techniques. Modified glassy carbon electrode of N-CQD/Cu2O/GCE is developed and is used for the sensor studies of aspirin. The modified N-CQD/Cu2O/GCE has exhibited a higher current (Ipa) response to the oxidation process when compared to N-CQD/GCE, Cu2O/GCE and bare GCE. Furthermore, it has shown a good linear range of 1-907 µM with a limit of detection (LOD) ∼0.002 µM and sensitivity ∼21.87 µA µM-1 cm-2. The developed sensor has displayed outstanding repeatability, stability and accumulation time along with better electro-catalytic response in berries for real-life application.