Younsu Kim1, Chloé Audigier1, Jens Ziegle2, Michael Friebe2, Emad M Boctor3. 1. Johns Hopkins University, 3400 N Charles Street, Baltimore, MD, 21218, USA. 2. Otto-von-Guericke University, Universitaetsplatz 2, 39106, Magdeburg, Saxony-Anhalt, Germany. 3. Johns Hopkins University, 3400 N Charles Street, Baltimore, MD, 21218, USA. eboctor1@jhmi.edu.
Abstract
PURPOSE: Thermotherapy is a clinical procedure which delivers thermal energy to a target, and it has been applied for various medical treatments. Temperature monitoring during thermotherapy is important to achieve precise and reproducible results. Medical ultrasound can be used for thermal monitoring and is an attractive medical imaging modality due to its advantages including non-ionizing radiation, cost-effectiveness and portability. We propose an ultrasound thermal monitoring method using a speed-of-sound tomographic approach coupled with a biophysical heat diffusion model. METHODS: We implement an ultrasound thermometry approach using an external ultrasound source. We reconstruct the speed-of-sound images using time-of-flight information from the external ultrasound source and convert the speed-of-sound information into temperature by using the a priori knowledge brought by a biophysical heat diffusion model. RESULTS: Customized treatment shapes can be created using switching channels of radio frequency bipolar needle electrodes. Simulations of various ablation lesion shapes in the temperature range of 21-59 [Formula: see text]C are performed to study the feasibility of the proposed method. We also evaluated our method with ex vivo porcine liver experiments, in which we generated temperature images between 22 and 45 [Formula: see text]C. CONCLUSION: In this paper, we present a proof of concept showing the feasibility of our ultrasound thermal monitoring method. The proposed method could be applied to various thermotherapy procedures by only adding an ultrasound source.
PURPOSE: Thermotherapy is a clinical procedure which delivers thermal energy to a target, and it has been applied for various medical treatments. Temperature monitoring during thermotherapy is important to achieve precise and reproducible results. Medical ultrasound can be used for thermal monitoring and is an attractive medical imaging modality due to its advantages including non-ionizing radiation, cost-effectiveness and portability. We propose an ultrasound thermal monitoring method using a speed-of-sound tomographic approach coupled with a biophysical heat diffusion model. METHODS: We implement an ultrasound thermometry approach using an external ultrasound source. We reconstruct the speed-of-sound images using time-of-flight information from the external ultrasound source and convert the speed-of-sound information into temperature by using the a priori knowledge brought by a biophysical heat diffusion model. RESULTS: Customized treatment shapes can be created using switching channels of radio frequency bipolar needle electrodes. Simulations of various ablation lesion shapes in the temperature range of 21-59 [Formula: see text]C are performed to study the feasibility of the proposed method. We also evaluated our method with ex vivo porcine liver experiments, in which we generated temperature images between 22 and 45 [Formula: see text]C. CONCLUSION: In this paper, we present a proof of concept showing the feasibility of our ultrasound thermal monitoring method. The proposed method could be applied to various thermotherapy procedures by only adding an ultrasound source.
Authors: Stephen Payne; Ronan Flanagan; Mika Pollari; Tuomas Alhonnoro; Claire Bost; David O'Neill; Tingying Peng; Philipp Stiegler Journal: Philos Trans A Math Phys Eng Sci Date: 2011-11-13 Impact factor: 4.226
Authors: Neb Duric; Norman Boyd; Peter Littrup; Mark Sak; Lukasz Myc; Cuiping Li; Erik West; Sal Minkin; Lisa Martin; Martin Yaffe; Steven Schmidt; Muhammad Faiz; Jason Shen; Olga Melnichouk; Qing Li; Teri Albrecht Journal: Med Phys Date: 2013-01 Impact factor: 4.071