H Nicole Tran1, Natalia Udaltsova2, Yan Li3, Arthur L Klatsky4. 1. Internist at the Oakland Medical Center in CA. nicole.h.tran@kp.org. 2. Data Consultant at the Division of Research in Oakland, CA. natalia.udaltsova@kp.org. 3. Hematologist and Oncologist at the Oakland Medical Center in CA. yan.li@kp.org. 4. Senior Consultant in Cardiology and an Adjunct Investigator in the Division of Research, Kaiser Permanente Medical Care Program, Oakland, CA. hartmavn@pacbell.net.
Abstract
CONTEXT: South Asians (ancestry in India, Pakistan, Bangladesh, or Sri Lanka) may have lower cancer risk than other racial-ethnic groups. OBJECTIVE: To supplement published cohort data suggesting low cancer risk in South Asians. DESIGN: Logistic regression models with 7 covariates to study cancer mortality through 2012 in 273,843 persons (1117 South Asians) with baseline examination data from 1964 to 1985. MAIN OUTCOME MEASURE: Cancer mortality. RESULTS: Through 2012, death was attributed to cancer in 28,031 persons, of which 1555 were Asians, including 32 South Asians. The all-Asian vs white adjusted odds ratio was 1.0, and the South Asian vs white odds ratio was 0.5 (p < 0.001). In separate regressions, South Asians were at lower risk than blacks, Chinese, Filipinos, Japanese, or other Asians. The South Asian-white disparity was concentrated in men but was generally similar when strata of smoking, body mass index, baseline age, and date of death were compared. CONCLUSION: These data support the observation that compared with whites and other Asian groups, South Asians, especially men, have a lower risk of cancer.
CONTEXT: South Asians (ancestry in India, Pakistan, Bangladesh, or Sri Lanka) may have lower cancer risk than other racial-ethnic groups. OBJECTIVE: To supplement published cohort data suggesting low cancer risk in South Asians. DESIGN: Logistic regression models with 7 covariates to study cancer mortality through 2012 in 273,843 persons (1117 South Asians) with baseline examination data from 1964 to 1985. MAIN OUTCOME MEASURE: Cancer mortality. RESULTS: Through 2012, death was attributed to cancer in 28,031 persons, of which 1555 were Asians, including 32 South Asians. The all-Asian vs white adjusted odds ratio was 1.0, and the South Asian vs white odds ratio was 0.5 (p < 0.001). In separate regressions, South Asians were at lower risk than blacks, Chinese, Filipinos, Japanese, or other Asians. The South Asian-white disparity was concentrated in men but was generally similar when strata of smoking, body mass index, baseline age, and date of death were compared. CONCLUSION: These data support the observation that compared with whites and other Asian groups, South Asians, especially men, have a lower risk of cancer.
Authors: K Vijayalakshmi; V Vettriselvi; M Krishnan; Sunil Shroff; K N Vishwanathan; Vikram R Jayanth; Solomon F D Paul Journal: Asian Pac J Cancer Prev Date: 2005 Jul-Sep
Authors: H Nicole Tran; Yan Li; Natalia Udaltsova; Mary Anne Armstrong; Gary D Friedman; Arthur L Klatsky Journal: Cancer Causes Control Date: 2016-08-25 Impact factor: 2.506
Authors: Nancy Krieger; Jarvis T Chen; Pamela D Waterman; David H Rehkopf; S V Subramanian Journal: Am J Public Health Date: 2003-10 Impact factor: 9.308
Authors: Camille Maringe; Punam Mangtani; Bernard Rachet; David A Leon; Michel P Coleman; Isabel dos Santos Silva Journal: Int J Cancer Date: 2012-10-12 Impact factor: 7.396