Inorganic Nano-Targeted Drugs Delivery System and Its Application of Platinum-Based Anticancer Drugs.

As one of the most important anticancer drugs, cisplatin and its analogues have been widely used in chemotherapy regimens of various tumors. However, a series of side effects and resistance/cross-resistance have been becoming the main obstacles which limit their application and effectiveness. Recent researches suggest that inorganic nano-materials which act as targeted drug delivery carriers of platinum-based anticancer drugs not only enhance the antitumor activity of platinum-based drugs, but also reduce the side effects and resistance. The nano-targeted drugs delivery system provides a new strategy in clinical application of platinum-based anticancer drugs. This review will focus on recent advances in inorganic nano-carriers for platinum-based targeted drugs delivery system.