Carmela Colica1, Laura Di Renzo2, Paola Gualtieri3, Lorenzo Romano4, Renata Costa de Miranda3, Antonino De Lorenzo2, Ivana Purificato5. 1. CNR, IBFM UOS, Università degli Studi "Magna Graecia" di Catanzaro, Campus "Salvatore Venuta", Germaneto, Catanzaro, Italy. 2. Sezione di Nutrizione Clinica e Nutrigenomica, Dipartimento di Biomedicina e Prevenzione, Università degli Studi di Roma "Tor Vergata", Rome, Italy. 3. Dottorato in Scienze Medico Chirurgiche Applicate, Università degli Studi di Roma "Tor Vergata", Rome, Italy. 4. Scuola di Specializzazione in Scienza dell'Alimentazione, Università degli Studi di Roma "Tor Vergata", Rome, Italy. 5. Dipartimento Sicurezza Alimentare, Nutrizione e Sanità Pubblica Veterinaria, Istituto Superiore di Sanità, Rome, Italy.
Abstract
AIM: To develop and cross-validate a predictive equation for estimating lean body mass (LBM) in children, based on bioelectrical impedance analysis (BIA) and anthropometric parameters, and to compare our equation with other predictive methods. METHODS: We evaluated body composition of 155 children (age 5-14 years) by BIA and dual energy X-ray absorptiometry (DXA). Children were divided in two groups: developing set and cross-validation set. Statistical analysis as multiple regression and Bland-Altman methods were performed. RESULTS: From developing set (105 children) a predictive LBM (kg) equation was created. From the cross-validated set (35 children), our equation was seen to agree with LBM (kg) by DXA. On the contrary, LBM predicted by Schaefer's equation and BIA did not agree with the criterion measure. CONCLUSIONS: This cross-validated equation can be useful in epidemiological studies and also in clinical practice, permitting a better definition and follow up of children's body composition.
AIM: To develop and cross-validate a predictive equation for estimating lean body mass (LBM) in children, based on bioelectrical impedance analysis (BIA) and anthropometric parameters, and to compare our equation with other predictive methods. METHODS: We evaluated body composition of 155 children (age 5-14 years) by BIA and dual energy X-ray absorptiometry (DXA). Children were divided in two groups: developing set and cross-validation set. Statistical analysis as multiple regression and Bland-Altman methods were performed. RESULTS: From developing set (105 children) a predictive LBM (kg) equation was created. From the cross-validated set (35 children), our equation was seen to agree with LBM (kg) by DXA. On the contrary, LBM predicted by Schaefer's equation and BIA did not agree with the criterion measure. CONCLUSIONS: This cross-validated equation can be useful in epidemiological studies and also in clinical practice, permitting a better definition and follow up of children's body composition.
Authors: Antonino De Lorenzo; Santo Gratteri; Paola Gualtieri; Andrea Cammarano; Pierfrancesco Bertucci; Laura Di Renzo Journal: J Transl Med Date: 2019-05-22 Impact factor: 5.531