Literature DB >> 29614688

Perseveration and Suicide in Huntington's Disease.

Olivia C Roman1, Jeffrey Stovall2, Daniel O Claassen3.   

Abstract

BACKGROUND: Huntington's disease (HD) patients are at significantly higher risk of suicidal behavior, and associated cognitive and behavioral factors play an important role. Impulsivity is commonly thought to be a risk factor, but does not completely account for all suicide attempts.
OBJECTIVE: To provide clinical evidence that perseverative behavior may precipitate suicide attempts in HD.
METHODS: Case review of four HD patients who attempted suicide.
RESULTS: Each patient demonstrated a clinical history of perseverative behavior, and endorsed perseveration on upsetting thoughts leading up to their suicide attempts. The attempts were planned in response to these ruminations.
CONCLUSIONS: The patients in this series experienced uncontrollable distressful thoughts prior to their thoughtfully planned suicide attempts. These patients did not appear to act impulsively in their decision to attempt suicide.

Entities:  

Keywords:  Huntington’s disease; perseveration; suicide

Mesh:

Year:  2018        PMID: 29614688     DOI: 10.3233/JHD-170249

Source DB:  PubMed          Journal:  J Huntingtons Dis        ISSN: 1879-6397


  2 in total

1.  Obsessive-Compulsive and Perseverative Behaviors in Huntington's Disease.

Authors:  Mayke Oosterloo; David Craufurd; Hanneke Nijsten; Erik van Duijn
Journal:  J Huntingtons Dis       Date:  2019

2.  Risk factors for suicidality in Huntington disease: An analysis of the 2CARE clinical trial.

Authors:  Andrew McGarry; Michael P McDermott; Karl Kieburtz; Wai Lun Alan Fung; Elizabeth McCusker; Jing Peng; Elisabeth A de Blieck; Merit Cudkowicz
Journal:  Neurology       Date:  2019-03-08       Impact factor: 9.910

  2 in total

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