Literature DB >> 29611511

Use of TaqMan Array Cards to Screen Outbreak Specimens for Causes of Febrile Illness in Tanzania.

Ahmed Abade1, Rachel B Eidex2, Athanasia Maro3, Jean Gratz4, Jie Liu4, Ireen Kiwelu3, Buliga Mujaga3, Maria E Kelly5, Blandina T Mmbaga3, James J Gibson2, Fausta Mosha5, Eric R Houpt4.   

Abstract

We describe the deployment of a custom-designed molecular diagnostic TaqMan Array Card (TAC) to screen for 31 bacterial, protozoal, and viral etiologies in blood from outbreaks of acute febrile illness in Tanzania during 2015-2017. On outbreaks notified to the Tanzanian Ministry of Health, epidemiologists were dispatched and specimens were collected, transported to a central national laboratory, and tested by TAC within 2 days. This algorithm streamlined investigation, diagnosed a typhoid outbreak, and excluded dozens of other etiologies. This method is usable in-country and may be incorporated into algorithms for diagnosing outbreaks.

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Year:  2018        PMID： 29611511      PMCID： PMC6086183          DOI： 10.4269/ajtmh.18-0071

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN： 0002-9637            Impact factor:   2.345


  8 in total

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Authors:  Jie Liu; Caroline Ochieng; Steve Wiersma; Ute Ströher; Jonathan S Towner; Shannon Whitmer; Stuart T Nichol; Christopher C Moore; Gilbert J Kersh; Cecilia Kato; Christopher Sexton; Jeannine Petersen; Robert Massung; Christine Hercik; John A Crump; Gibson Kibiki; Athanasia Maro; Buliga Mujaga; Jean Gratz; Shevin T Jacob; Patrick Banura; W Michael Scheld; Bonventure Juma; Clayton O Onyango; Joel M Montgomery; Eric Houpt; Barry Fields
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3.  Development and assessment of molecular diagnostic tests for 15 enteropathogens causing childhood diarrhoea: a multicentre study.

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8.  Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study.

Authors:  Jie Liu; James A Platts-Mills; Jane Juma; Furqan Kabir; Joseph Nkeze; Catherine Okoi; Darwin J Operario; Jashim Uddin; Shahnawaz Ahmed; Pedro L Alonso; Martin Antonio; Stephen M Becker; William C Blackwelder; Robert F Breiman; Abu S G Faruque; Barry Fields; Jean Gratz; Rashidul Haque; Anowar Hossain; M Jahangir Hossain; Sheikh Jarju; Farah Qamar; Najeeha Talat Iqbal; Brenda Kwambana; Inacio Mandomando; Timothy L McMurry; Caroline Ochieng; John B Ochieng; Melvin Ochieng; Clayton Onyango; Sandra Panchalingam; Adil Kalam; Fatima Aziz; Shahida Qureshi; Thandavarayan Ramamurthy; James H Roberts; Debasish Saha; Samba O Sow; Suzanne E Stroup; Dipika Sur; Boubou Tamboura; Mami Taniuchi; Sharon M Tennant; Deanna Toema; Yukun Wu; Anita Zaidi; James P Nataro; Karen L Kotloff; Myron M Levine; Eric R Houpt
Journal:  Lancet       Date:  2016-09-24       Impact factor: 79.321
  8 in total
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3.  Development and Implementation of Multiplex TaqMan Array Cards for Specimen Testing at Child Health and Mortality Prevention Surveillance Site Laboratories.

Authors:  Maureen H Diaz; Jessica L Waller; M Jordan Theodore; Nishi Patel; Bernard J Wolff; Alvaro J Benitez; Timothy Morris; Pratima L Raghunathan; Robert F Breiman; Cynthia G Whitney; Dianna M Blau; Jonas M Winchell
Journal:  Clin Infect Dis       Date:  2019-10-09       Impact factor: 9.079

4.  Etiology of Pediatric Meningitis in West Africa Using Molecular Methods in the Era of Conjugate Vaccines against Pneumococcus, Meningococcus, and Haemophilus influenzae Type b.

Authors:  Brenda A Kwambana-Adams; Jie Liu; Catherine Okoi; Jason M Mwenda; Nuredin I Mohammed; Enyonam Tsolenyanu; Lorna Awo Renner; Daniel Ansong; Beckie N Tagbo; Muhammad F Bashir; Mamadou Kourna Hama; Mouhamadou A Sonko; Jean Gratz; Archibald Worwui; Peter Ndow; Adam L Cohen; Fatima Serhan; Richard Mihigo; Martin Antonio; Eric Houpt
Journal:  Am J Trop Med Hyg       Date:  2020-05-21       Impact factor: 2.345

5.  First laboratory confirmation and sequencing of Zaire ebolavirus in Uganda following two independent introductions of cases from the 10th Ebola Outbreak in the Democratic Republic of the Congo, June 2019.

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7.  Pathogens That Cause Acute Febrile Illness Among Children and Adolescents in Burkina Faso, Madagascar, and Sudan.

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