Literature DB >> 29611500

A Randomized Controlled Trial to Assess the Impact of Ceramic Water Filters on Prevention of Diarrhea and Cryptosporidiosis in Infants and Young Children-Western Kenya, 2013.

Jamae Fontain Morris1,2,3, Jennifer Murphy3, Kirsten Fagerli3, Chandra Schneeberger3, Peter Jaron4, Fenny Moke4, Jane Juma4, John B Ochieng4, Richard Omore4, Dawn Roellig3, Lihua Xiao3, Jeffrey W Priest3, Jothikumar Narayanan3, Joel M Montgomery5, Vince Hill3, Eric Mintz3, Tracy L Ayers3, Ciara E O'Reilly3.   

Abstract

Cryptosporidium is a leading cause of diarrhea among Kenyan infants. Ceramic water filters (CWFs) are used for household water treatment. We assessed the impact of CWFs on diarrhea, cryptosporidiosis prevention, and water quality in rural western Kenya. A randomized, controlled intervention trial was conducted in 240 households with infants 4-10 months old. Twenty-six weekly household surveys assessed infant diarrhea and health facility visits. Stool specimens from infants with diarrhea were examined for Cryptosporidium. Source water, filtered water, and filter retentate were tested for Cryptosporidium and/or microbial indicators. To estimate the effect of CWFs on health outcomes, logistic regression models using generalized estimating equations were performed; odds ratios (ORs) and 95% confidence intervals (CIs) are reported. Households reported using surface water (36%), public taps (29%), or rainwater (17%) as their primary drinking water sources, with no differences in treatment groups. Intervention households reported less diarrhea (7.6% versus 8.9%; OR: 0.86 [0.64-1.16]) and significantly fewer health facility visits for diarrhea (1.0% versus 1.9%; OR: 0.50 [0.30-0.83]). In total, 15% of intervention and 12% of control stools yielded Cryptosporidium (P = 0.26). Escherichia coli was detected in 93% of source water samples; 71% of filtered water samples met World Health Organization recommendations of < 1 E. coli/100 mL. Cryptosporidium was not detected in source water and was detected in just 2% of filter rinses following passage of large volumes of source water. Water quality was improved among CWF users; however, the short study duration and small sample size limited our ability to observe reductions in cryptosporidiosis.

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Year:  2018        PMID: 29611500      PMCID: PMC5953370          DOI: 10.4269/ajtmh.17-0731

Source DB:  PubMed          Journal:  Am J Trop Med Hyg        ISSN: 0002-9637            Impact factor:   2.345


  48 in total

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Review 4.  Effect of sanitation and water treatment on intestinal protozoa infection: a systematic review and meta-analysis.

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Journal:  Lancet Infect Dis       Date:  2015-09-21       Impact factor: 25.071

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7.  Detection and differentiation of Cryptosporidium hominis and Cryptosporidium parvum by dual TaqMan assays.

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8.  Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000.

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9.  Health care-seeking behavior during childhood diarrheal illness: results of health care utilization and attitudes surveys of caretakers in western Kenya, 2007-2010.

Authors:  Richard Omore; Ciara E O'Reilly; John Williamson; Fenny Moke; Vincent Were; Tamer H Farag; Anna Maria van Eijk; Karen L Kotloff; Myron M Levine; David Obor; Frank Odhiambo; John Vulule; Kayla F Laserson; Eric D Mintz; Robert F Breiman
Journal:  Am J Trop Med Hyg       Date:  2013-04-29       Impact factor: 2.345

10.  Selecting a sample size for studies with repeated measures.

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Journal:  Elife       Date:  2019-08-19       Impact factor: 8.140

2.  Emerging Trends in Clinical Tropical Medicine Research.

Authors:  Mark K Huntington; Joe P Bryan; Troy D Moon; Pascal J Imperato; Susan L F McLellan; Walter R Taylor; John S Schieffelin
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3.  From Water Source to Tap of Ceramic Filters-Factors That Influence Water Quality Between Collection and Consumption in Rural Households in Nepal.

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Review 4.  Cryptosporidium Infections in Africa-How Important Is Zoonotic Transmission? A Review of the Evidence.

Authors:  Lucy J Robertson; Øystein Haarklau Johansen; Tsegabirhan Kifleyohannes; Akinwale Michael Efunshile; Getachew Terefe
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5.  Only Low Effects of Water Filters on the Enteric Carriage of Gastrointestinal Pathogen DNA in Colombian Indigenous People.

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Journal:  Microorganisms       Date:  2022-03-19
  5 in total

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