Literature DB >> 29611146

A care bundle to improve perioperative mitomycin use in non-muscle-invasive bladder cancer.

Deepak Batura1, Tumaj Hashemzehi2, Josie Colemeadow2.   

Abstract

PURPOSE: Intravesical chemotherapy administered within 24 h of the first resection of non-muscle-invasive bladder cancer (NMIBC) reduces recurrence rates and prolongs recurrence-free intervals. However, there is considerable variation in the use of intravesical chemotherapy amongst urologists. In our hospital, we use mitomycin C (MMC), and our usage was inconsistent. Therefore, we devised a care bundle to improve MMC usage. The objective of this study was to evaluate the effectiveness of the care bundle on postoperative MMC use.
METHODS: We measured baseline postoperative MMC use during the first quarter of 2013. In 2014, we implemented a care bundle by changing MMC delivery, through computer-based clinical information systems and repeated training of key stakeholders. We studied the performance of the bundle through snapshot audits in the last quarter of 2014, a 6-month period in the middle of 2015 and again in the final quarter of 2016.
RESULTS: We observed an increase in intravesical chemotherapy usage after implementing the care bundle. Instillation rates in our samples increased from 46% (6/13), in 2013 to 89% (8/9), in 2014, 90% (9/10), in 2015 and 100% (12/12), in 2016.
CONCLUSION: Compliance rates of intravesical chemotherapy in NMIBC can improve by devising care bundles to modify team behaviour.

Entities:  

Keywords:  Care bundle; Chemotherapy; Intravesical instillation; Mitomycin C; Non-muscle-invasive bladder cancer

Mesh:

Substances:

Year:  2018        PMID: 29611146     DOI: 10.1007/s11255-018-1863-4

Source DB:  PubMed          Journal:  Int Urol Nephrol        ISSN: 0301-1623            Impact factor:   2.370


  24 in total

Review 1.  A review of current guidelines and best practice recommendations for the management of nonmuscle invasive bladder cancer by the International Bladder Cancer Group.

Authors:  Maurizio Brausi; J Alfred Witjes; Donald Lamm; Raj Persad; Joan Palou; Marc Colombel; Roger Buckley; Mark Soloway; Hideyuki Akaza; Andreas Böhle
Journal:  J Urol       Date:  2011-10-19       Impact factor: 7.450

2.  Value of an Immediate Intravesical Instillation of Mitomycin C in Patients with Non-muscle-invasive Bladder Cancer: A Prospective Multicentre Randomised Study in 2243 patients.

Authors:  Judith Bosschieter; Jakko A Nieuwenhuijzen; Tessa van Ginkel; André N Vis; Birgit Witte; Don Newling; Goedele M A Beckers; R Jeroen A van Moorselaar
Journal:  Eur Urol       Date:  2017-07-10       Impact factor: 20.096

3.  Methods to improve efficacy of intravesical mitomycin C: results of a randomized phase III trial.

Authors:  J L Au; R A Badalament; M G Wientjes; D C Young; J A Warner; P L Venema; D L Pollifrone; J D Harbrecht; J L Chin; S P Lerner; B J Miles
Journal:  J Natl Cancer Inst       Date:  2001-04-18       Impact factor: 13.506

4.  Intravesical gemcitabine in combination with mitomycin C as salvage treatment in recurrent non-muscle-invasive bladder cancer.

Authors:  Patrick A Cockerill; John J Knoedler; Igor Frank; Robert Tarrell; Robert J Karnes
Journal:  BJU Int       Date:  2015-05-23       Impact factor: 5.588

Review 5.  EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013.

Authors:  Marko Babjuk; Maximilian Burger; Richard Zigeuner; Shahrokh F Shariat; Bas W G van Rhijn; Eva Compérat; Richard J Sylvester; Eero Kaasinen; Andreas Böhle; Joan Palou Redorta; Morgan Rouprêt
Journal:  Eur Urol       Date:  2013-06-12       Impact factor: 20.096

Review 6.  Systematic Review and Individual Patient Data Meta-analysis of Randomized Trials Comparing a Single Immediate Instillation of Chemotherapy After Transurethral Resection with Transurethral Resection Alone in Patients with Stage pTa-pT1 Urothelial Carcinoma of the Bladder: Which Patients Benefit from the Instillation?

Authors:  Richard J Sylvester; Willem Oosterlinck; Sten Holmang; Matthew R Sydes; Alison Birtle; Sigurdur Gudjonsson; Cosimo De Nunzio; Kikuo Okamura; Eero Kaasinen; Eduardo Solsona; Bedeir Ali-El-Dein; Can Ali Tatar; Brant A Inman; James N'Dow; Jorg R Oddens; Marek Babjuk
Journal:  Eur Urol       Date:  2015-06-16       Impact factor: 20.096

7.  Compliance with guidelines for patients with bladder cancer: variation in the delivery of care.

Authors:  Karim Chamie; Christopher S Saigal; Julie Lai; Jan M Hanley; Claude M Setodji; Badrinath R Konety; Mark S Litwin
Journal:  Cancer       Date:  2011-07-11       Impact factor: 6.860

8.  Treatment of nonmuscle invading bladder cancer: do physicians in the United States practice evidence based medicine? The use and economic implications of intravesical chemotherapy after transurethral resection of bladder tumors.

Authors:  Ralph Madeb; Dragan Golijanin; Katia Noyes; Susan Fisher; Judith J Stephenson; Stacey R Long; Joy Knopf; Gary H Lyman; Edward M Messing
Journal:  Cancer       Date:  2009-06-15       Impact factor: 6.860

9.  Pathobiology and chemoprevention of bladder cancer.

Authors:  Takuji Tanaka; Katsuhito Miyazawa; Tetsuya Tsukamoto; Toshiya Kuno; Koji Suzuki
Journal:  J Oncol       Date:  2011-09-15       Impact factor: 4.375

10.  Clinical Practice Pattern of Immediate Intravesical Chemotherapy following Transurethral Resection of a Bladder Tumor in Korea: National Health Insurance Database Study.

Authors:  Gi Hyeon Seo; Jae Heon Kim; Ja Hyeon Ku
Journal:  Sci Rep       Date:  2016-03-15       Impact factor: 4.379

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  1 in total

1.  Redefining the role of immediate intravesical instillation of mitomycin C in non-muscle invasive bladder cancer.

Authors:  Deepak Batura
Journal:  Transl Androl Urol       Date:  2018-12
  1 in total

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