Literature DB >> 29610810

An organocatalytic enantioselective direct α-heteroarylation of aldehydes with isoquinoline N-oxides.

Giulio Bertuzzi1, Daniel Pecorari, Luca Bernardi, Mariafrancesca Fochi.   

Abstract

A new protocol for the enantioselective direct α-heteroarylation of aldehydes with isoquinoline N-oxides, via chiral enamine catalysis, has been successfully developed. High enantiomeric excesses and moderate to good yields were achieved for a variety of α-heteroarylated aldehydes.

Entities:  

Year:  2018        PMID: 29610810     DOI: 10.1039/c8cc01735b

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  3 in total

1.  A novel and robust heterogeneous Cu catalyst using modified lignosulfonate as support for the synthesis of nitrogen-containing heterocycles.

Authors:  Bingbing Lai; Meng Ye; Ping Liu; Minghao Li; Rongxian Bai; Yanlong Gu
Journal:  Beilstein J Org Chem       Date:  2020-11-26       Impact factor: 2.883

2.  Sulfoxonium Ylides in Aminocatalysis: An Enantioselective Entry to Cyclopropane-Fused Chromanol Structures.

Authors:  Giorgiana Denisa Bisag; Pietro Pecchini; Michele Mancinelli; Mariafrancesca Fochi; Luca Bernardi
Journal:  Org Lett       Date:  2022-07-20       Impact factor: 6.072

3.  Phosphite mediated asymmetric N to C migration for the synthesis of chiral heterocycles from primary amines.

Authors:  Soniya Rani; Soumya Ranjan Dash; Asish Bera; Md Nirshad Alam; Kumar Vanka; Pradip Maity
Journal:  Chem Sci       Date:  2021-05-28       Impact factor: 9.825

  3 in total

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