Literature DB >> 2961007

Human recombinant lipocortin 1 inhibits prostacyclin production by human umbilical artery in vitro.

G Cirino1, R J Flower.   

Abstract

Submicromolar concentrations of human recombinant Lipocortin 1 inhibit the release of prostacyclin from human umbilical artery rings in a dose-dependent fashion. This is the first demonstration that the recombinant protein is effective in human cells.

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Year:  1987        PMID： 2961007     DOI： 10.1016/0090-6980(87)90262-0

Source DB:  PubMed          Journal:  Prostaglandins        ISSN： 0090-6980


  21 in total

1.  Annexin A1 regulates intestinal mucosal injury, inflammation, and repair.

Authors:  Brian A Babbin; Mike G Laukoetter; Porfirio Nava; Stefan Koch; Winston Y Lee; Christopher T Capaldo; Eric Peatman; Eric A Severson; Roderick J Flower; Mauro Perretti; Charles A Parkos; Asma Nusrat
Journal:  J Immunol       Date:  2008-10-01       Impact factor: 5.422

Review 2.  Eleventh Gaddum memorial lecture. Lipocortin and the mechanism of action of the glucocorticoids.

Authors:  R J Flower
Journal:  Br J Pharmacol       Date:  1988-08       Impact factor: 8.739

3.  Anti-inflammatory actions of an N-terminal peptide from human lipocortin 1.

Authors:  G Cirino; C Cicala; L Sorrentino; G Ciliberto; G Arpaia; M Perretti; R J Flower
Journal:  Br J Pharmacol       Date:  1993-03       Impact factor: 8.739

Review 4.  New insights into the mode of action of anti-inflammatory drugs.

Authors:  J R Vane; R M Botting
Journal:  Inflamm Res       Date:  1995-01       Impact factor: 4.575

5.  Human recombinant lipocortin 1 has acute local anti-inflammatory properties in the rat paw edema test.

Authors:  G Cirino; S H Peers; R J Flower; J L Browning; R B Pepinsky
Journal:  Proc Natl Acad Sci U S A       Date:  1989-05       Impact factor: 11.205

6.  Annexin-1 peptide Anx-1(2-26) protects adult rat cardiac myocytes from cellular injury induced by simulated ischaemia.

Authors:  Rebecca H Ritchie; Jennifer M Gordon; Owen L Woodman; Anh H Cao; Gregory J Dusting
Journal:  Br J Pharmacol       Date:  2005-06       Impact factor: 8.739

7.  Biphasic regulation by dexamethasone of IL-1- and LPS-stimulated endothelial prostacyclin production.

Authors:  G Prajgrod; A Danon
Journal:  Agents Actions       Date:  1992-03

8.  Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line.

Authors:  J D Croxtall; R J Flower
Journal:  Proc Natl Acad Sci U S A       Date:  1992-04-15       Impact factor: 11.205

9.  Effect of dexamethasone on neutrophil accumulation and oedema formation in rabbit skin: an investigation of site of action.

Authors:  H Yarwood; S Nourshargh; S Brain; T J Williams
Journal:  Br J Pharmacol       Date:  1993-04       Impact factor: 8.739

10.  Dexamethasone induces an increase in intracellular and membrane-associated lipocortin-1 (annexin-1) in rat astrocyte primary cultures.

Authors:  J D McLeod; C Bolton
Journal:  Cell Mol Neurobiol       Date:  1995-04       Impact factor: 5.046
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