Literature DB >> 2960738

Expression of T cell antigen receptor beta-chains on subsets of mouse thymocytes. Analysis by three-color flow cytometry.

I N Crispe1, R P Shimonkevitz, L A Husmann, J Kimura, J P Allison.   

Abstract

The expression on adult mouse thymocytes of a T cell antigen receptor beta-chain epitope, recognized by the antibody F23.1, has been studied by three-color flow cytometry. Low density F23.1 staining was found mainly on CD4+8+ thymocytes. High density staining was mainly on CD4+8- and CD4-8+ cells. Variable proportions of CD4-8- cells were also F23.1+. Among CD4-8+ cells, F23.1 was expressed only on the J11d- subset with mature T cell function. We conclude that many subpopulations of thymocytes express antigen receptors and are candidates for the population subject to thymic selection, but at present no single subpopulation makes a convincing claim.

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Year:  1987        PMID： 2960738

Source DB:  PubMed          Journal:  J Immunol        ISSN： 0022-1767            Impact factor:   5.422


  6 in total

1.  CD8αα and -αβ isotypes are equally recruited to the immunological synapse through their ability to bind to MHC class I.

Authors:  Vasily Rybakin; Jean-Pierre Clamme; Jeanette Ampudia; Pia P Yachi; Nicholas R J Gascoigne
Journal:  EMBO Rep       Date:  2011-12-01       Impact factor: 8.807

Review 2.  Phenotypic analysis of mouse thymus development.

Authors:  R Ceredig; F Lynch; J Medveczky
Journal:  Immunol Res       Date:  1988       Impact factor: 2.829

3.  CD3 eta and CD3 zeta are alternatively spliced products of a common genetic locus and are transcriptionally and/or post-transcriptionally regulated during T-cell development.

Authors:  L K Clayton; L D'Adamio; F D Howard; M Sieh; R E Hussey; S Koyasu; E L Reinherz
Journal:  Proc Natl Acad Sci U S A       Date:  1991-06-15       Impact factor: 11.205

4.  A special repertoire of alpha:beta T cells in neonatal mice.

Authors:  M Bogue; S Candéias; C Benoist; D Mathis
Journal:  EMBO J       Date:  1991-12       Impact factor: 11.598

5.  Preferential expression of fibronectin receptors on immature thymocytes.

Authors:  P M Cardarelli; I N Crispe; M D Pierschbacher
Journal:  J Cell Biol       Date:  1988-06       Impact factor: 10.539

6.  T cell activation enhancement by endogenous pMHC acts for both weak and strong agonists but varies with differentiation state.

Authors:  Pia P Yachi; Carina Lotz; Jeanette Ampudia; Nicholas R J Gascoigne
Journal:  J Exp Med       Date:  2007-10-22       Impact factor: 14.307
  6 in total

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