Literature DB >> 29606996

Structural Changes of Subcutaneous Tissue Valued by Ultrasonography in Patients with Cellulitis Following Treatment with the PnKCelulitis® Program.

Esther Roe1,2, Esther Serra1,2, German Guzman1,2, Ignacio Sajoux1,2.   

Abstract

Background: Poor eating habits, a sedentary lifestyle, and limited physical activity are predisposing factors for the development of cellulite. The PnKCelulitis® Programme (Pronokal Group, Barcelona, Spain) is a new approach to the treatment of cellulite that combines dietary guidelines, physical exercise, and the application of an anti-cellulite cream. Objective: We sought to objectively and via cutaneous ultrasound assess the benefit of the new multidisciplinary anti-cellulite treatment program and to evaluate any visual changes in the appearance of the skin. Materials and methods: Twenty women with Grades 1 to 3 cellulite were included in the study. All women underwent the multidisciplinary treatment. Clinical controls assessed the evolution of the degree of cellulite; the anthropometric parameters (e.g., weight, body mass index, and mean and low abdominal circumference) and body composition were assessed by bioimpedance. Ultrasound assessments were performed blinded at the beginning and at the end of treatment to assess the following: thickness of the skin, dermis, and hypodermis; areas of indentation; and changes in the echogenicity of the dermis.
Results: The degree of cellulite was reduced in all locations, and 90 percent (18/20) of the sample saw their cellulite reduced by at least one degree. Cellulite in the abdomen disappeared in all of the women who had initially presented with it. Most of the subjects with cellulite in the buttocks (70%, 13/19) completed the treatment with Grade 0. There was a decrease in weight and a reduction of abdominal perimeters at the expense of only body fat. Significant decreases in the thickness of the skin and hypodermis and in areas of indentation were observed (p<0.05), in addition to an increase in the echogenicity of the dermis in 18 of the 20 patients. Conclusions: The multidisciplinary treatment program evaluated in this study appears to be an effective and safe treatment for patients with different degrees of cellulite, both clinically and via ultrasound imaging. Additional research with a larger patient cohort is needed to support our findings.

Entities:  

Keywords:  Cellulite; PnKCelulitis®; adipose tissue; therapeutics; ultrasonography

Year:  2018        PMID: 29606996      PMCID: PMC5868780     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  18 in total

1.  Circumference reduction and cellulite treatment with a TriPollar radiofrequency device: a pilot study.

Authors:  W Manuskiatti; C Wachirakaphan; N Lektrakul; S Varothai
Journal:  J Eur Acad Dermatol Venereol       Date:  2009-04-08       Impact factor: 6.166

Review 2.  A modern approach to the treatment of cellulite.

Authors:  Anthony M Rossi; Bruce E Katz
Journal:  Dermatol Clin       Date:  2014-01       Impact factor: 3.478

Review 3.  Carnitine biosynthesis in mammals.

Authors:  Frédéric M Vaz; Ronald J A Wanders
Journal:  Biochem J       Date:  2002-02-01       Impact factor: 3.857

4.  Imaging of the skin and subcutaneous tissue using classical and high-frequency ultrasonographies in anti-cellulite therapy.

Authors:  Robert Krzysztof Mlosek; Renata Maria Dębowska; Marcin Lewandowski; Sylwia Malinowska; Andrzej Nowicki; Irena Eris
Journal:  Skin Res Technol       Date:  2011-02-21       Impact factor: 2.365

Review 5.  Extracorporeal shockwave: mechanisms of action and physiological aspects for cellulite, body shaping, and localized fat-Systematic review.

Authors:  Débora A Oliveira Modena; Caroline Nogueira da Silva; Clovis Grecco; Renata Michelini Guidi; Renata Gomes Moreira; Andresa A Coelho; Estela Sant'Ana; José Ricardo de Souza
Journal:  J Cosmet Laser Ther       Date:  2017-06-07       Impact factor: 2.247

6.  Effect of controlled volumetric tissue heating with radiofrequency on cellulite and the subcutaneous tissue of the buttocks and thighs.

Authors:  Ma Emilia del Pino; Ramón H Rosado; Alejandro Azuela; Ma Graciela Guzmán; Dinorah Argüelles; Carlos Rodríguez; Gesche M Rosado
Journal:  J Drugs Dermatol       Date:  2006-09       Impact factor: 2.114

7.  Inhibition of adipocyte differentiation by mechanical stretching through ERK-mediated downregulation of PPARgamma2.

Authors:  Yoshiyuki Tanabe; Masaru Koga; Maki Saito; Yumi Matsunaga; Koichi Nakayama
Journal:  J Cell Sci       Date:  2004-07-15       Impact factor: 5.285

8.  A multicenter study of cellulite treatment with a variable emission radio frequency system.

Authors:  Claudia van der Lugt; Carmen Romero; Dvora Ancona; Marwan Al-Zarouni; Joanet Perera; Mario A Trelles
Journal:  Dermatol Ther       Date:  2009 Jan-Feb       Impact factor: 2.851

9.  Anatomy and physiology of subcutaneous adipose tissue by in vivo magnetic resonance imaging and spectroscopy: relationships with sex and presence of cellulite.

Authors:  B Querleux; C Cornillon; O Jolivet; J Bittoun
Journal:  Skin Res Technol       Date:  2002-05       Impact factor: 2.365

Review 10.  Cellulite in menopause.

Authors:  Marta Leszko
Journal:  Prz Menopauzalny       Date:  2014-11-02
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