Literature DB >> 29606721

Successful management of lymphangiosarcoma in a puppy using a tyrosine kinase inhibitor.

Ji-Hyun Kim1, Hakyoung Yoon1, Hun-Young Yoon1, Kidong Eom1, Hyun-Jeong Sung1, Jung-Hyun Kim1.   

Abstract

A puppy was diagnosed with lymphangiosarcoma associated with lymphedema based on lymphography and histopathology. The lesions resolved after toceranib therapy, and the dog remains in remission 1 year later. This is the first report of a successful outcome following oral toceranib as first-line therapy for lymphangiosarcoma in a dog.

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Year:  2018        PMID： 29606721      PMCID： PMC5855224     

Source DB:  PubMed          Journal:  Can Vet J        ISSN： 0008-5286            Impact factor:   1.008


  22 in total

1.  Lymphangiosarcoma associated with primary lymphedema in a Bouvier des Flandres.

Authors:  Jinelle A Webb; Sarah E Boston; Julie Armstrong; Noel M M Moens
Journal:  J Vet Intern Med       Date:  2004 Jan-Feb       Impact factor: 3.333

Review 2.  Receptor tyrosine kinase inhibitors: molecularly targeted drugs for veterinary cancer therapy.

Authors:  S Bavcar; D J Argyle
Journal:  Vet Comp Oncol       Date:  2012-09       Impact factor: 2.613

3.  Safety evaluation of combination CCNU and continuous toceranib phosphate (Palladia(®) ) in tumour-bearing dogs: a phase I dose-finding study.

Authors:  X Pan; K Tsimbas; I D Kurzman; D M Vail
Journal:  Vet Comp Oncol       Date:  2014-04-16       Impact factor: 2.613

4.  Principles of surgical treatment of chronic lymphoedema.

Authors:  P Gloviczki
Journal:  Int Angiol       Date:  1999-03       Impact factor: 2.789

5.  Lymphangiosarcoma in 12 dogs: a case series (1998-2013).

Authors:  K M Curran; C H C Halsey; D R Worley
Journal:  Vet Comp Oncol       Date:  2014-02-26       Impact factor: 2.613

6.  Use of surgery and mitoxantrone chemotherapy in a dog with disseminated lymphangiosarcoma.

Authors:  Véronique Sicotte; Jérôme Benamou; Lyanne C Fifle; Jérôme Planté; Hugues I Lacoste; Hugo Joly; Adam W Stern
Journal:  J Am Vet Med Assoc       Date:  2012-12-15       Impact factor: 1.936

7.  Lack of effect of coumarin in women with lymphedema after treatment for breast cancer.

Authors:  C L Loprinzi; J W Kugler; J A Sloan; T W Rooke; S K Quella; P Novotny; R B Mowat; J C Michalak; P J Stella; R Levitt; L K Tschetter; H Windschitl
Journal:  N Engl J Med       Date:  1999-02-04       Impact factor: 91.245

Review 8.  Lymphedema. Clinical signs, diagnosis, and treatment.

Authors:  T W Fossum; L A King; M W Miller; L M Butler
Journal:  J Vet Intern Med       Date:  1992 Nov-Dec       Impact factor: 3.333

9.  Treatment of lymphedema of the arms and legs with 5,6-benzo-[alpha]-pyrone.

Authors:  J R Casley-Smith; R G Morgan; N B Piller
Journal:  N Engl J Med       Date:  1993-10-14       Impact factor: 91.245

10.  Evaluation of the adverse event profile and pharmacodynamics of toceranib phosphate administered to dogs with solid tumors at doses below the maximum tolerated dose.

Authors:  Luis Feo Bernabe; Roberta Portela; Sandra Nguyen; William C Kisseberth; Michael Pennell; Mark F Yancey; Cheryl A London
Journal:  BMC Vet Res       Date:  2013-09-30       Impact factor: 2.741
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  1 in total

1.  Pathologic and flow cytometric features of a case of canine ventral cervical lymphangiosarcoma.

Authors:  Carolina N Azevedo; Allyson A Sterman; Lauren W Stranahan; Brianne M Taylor; Dominique J Wiener; Jacqueline R Davidson; Karen E Russell
Journal:  J Vet Diagn Invest       Date:  2020-04-20       Impact factor: 1.279
  1 in total

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