Literature DB >> 2960665

Mutational analysis of the lambda int gene: DNA sequence of dominant mutations.

S E Bear1, J B Clemens, L W Enquist, R J Zagursky.   

Abstract

We have combined techniques of genetic and physical mapping with rapid DNA sequence analysis to identify the nucleotide change in lambda int mutations. These mutations define two dominant phenotypic classes: (i) recombination that is partially independent of accessory factors, and (ii) inhibition of wild-type Int by missense or nonsense proteins, i.e., negative complementation.

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Year:  1987        PMID： 2960665      PMCID： PMC214194          DOI： 10.1128/jb.169.12.5880-5883.1987

Source DB:  PubMed          Journal:  J Bacteriol        ISSN： 0021-9193            Impact factor:   3.490


  15 in total

1.  The nature and origin of a class of essential gene substitutions in bacteriophage lambda.

Authors:  D Henderson; J Weil
Journal:  Virology       Date:  1975-09       Impact factor: 3.616

2.  The red plaque test: a rapid method for identification of excision defective variants of bacteriophage lambda.

Authors:  L W Enquist; R A Weisberg
Journal:  Virology       Date:  1976-07-01       Impact factor: 3.616

3.  Mutants of bacteriophage lambda unable to integrate into the host chromosome.

Authors:  R Gingery; H Echols
Journal:  Proc Natl Acad Sci U S A       Date:  1967-10       Impact factor: 11.205

4.  Nonessential functions of bacteriophage lambda.

Authors:  K F Manly; E R Signer; C M Radding
Journal:  Virology       Date:  1969-02       Impact factor: 3.616

5.  Deletion mutants of bacteriophage lambda. 3. Physical structure of att-phi.

Authors:  R W Davis; J S Parkinson
Journal:  J Mol Biol       Date:  1971-03-14       Impact factor: 5.469

6.  A genetic analysis of the att-int-xis region of coliphage lambda.

Authors:  L W Enquist; R A Weisberg
Journal:  J Mol Biol       Date:  1977-04       Impact factor: 5.469

7.  Regulation of integration by coliphage lambda: activation of int transcription by the cII and cIII proteins.

Authors:  A Honigman; S L Hu; W Szybalski
Journal:  Virology       Date:  1979-01-30       Impact factor: 3.616

8.  Integration-negative (int) mutants of phage lambda.

Authors:  J Zissler
Journal:  Virology       Date:  1967-01       Impact factor: 3.616

9.  Nicking-closing activity associated with bacteriophage lambda int gene product.

Authors:  Y Kikuchi; H A Nash
Journal:  Proc Natl Acad Sci U S A       Date:  1979-08       Impact factor: 11.205

10.  The mechanism of phage lambda site-specific recombination: site-specific breakage of DNA by Int topoisomerase.

Authors:  N L Craig; H A Nash
Journal:  Cell       Date:  1983-12       Impact factor: 41.582
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  7 in total

1.  Two structural features of lambda integrase that are critical for DNA cleavage by multimers but not by monomers.

Authors:  Sang Yeol Lee; Hideki Aihara; Tom Ellenberger; Arthur Landy
Journal:  Proc Natl Acad Sci U S A       Date:  2004-02-19       Impact factor: 11.205

2.  Nucleotide sequence and genetic characterization of staphylococcal bacteriophage L54a int and xis genes.

Authors:  Z H Ye; C Y Lee
Journal:  J Bacteriol       Date:  1989-08       Impact factor: 3.490

3.  A point mutation in the Nul gene of bacteriophage lambda facilitates phage growth in Escherichia coli with himA and gyrB mutations.

Authors:  A E Granston; D M Alessi; L J Eades; D I Friedman
Journal:  Mol Gen Genet       Date:  1988-04

4.  An intermediate in the phage lambda site-specific recombination reaction is revealed by phosphorothioate substitution in DNA.

Authors:  P A Kitts; H A Nash
Journal:  Nucleic Acids Res       Date:  1988-07-25       Impact factor: 16.971

5.  Receipt of the C-terminal tail from a neighboring lambda Int protomer allosterically stimulates Holliday junction resolution.

Authors:  Dane Hazelbaker; Marta Radman-Livaja; Arthur Landy
Journal:  J Mol Biol       Date:  2005-09-02       Impact factor: 5.469

6.  Integration host factor of Escherichia coli reverses the inhibition of R6K plasmid replication by pi initiator protein.

Authors:  S Dellis; M Filutowicz
Journal:  J Bacteriol       Date:  1991-02       Impact factor: 3.490

7.  Synaptic intermediates in bacteriophage lambda site-specific recombination: integrase can align pairs of attachment sites.

Authors:  A M Segall; H A Nash
Journal:  EMBO J       Date:  1993-12       Impact factor: 11.598
  7 in total

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