Ademola Olusegun Talabi1, Oludayo Adedapo Sowande2, Anthony Taiwo Adenekan3, Olusanya Adejuyigbe4, Collins Chijioke Adumah5, Arua Obasi Igwe6. 1. Department Of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun State, Nigeria. Electronic address: ademolatalabi1608@gmail.com. 2. Department Of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun State, Nigeria. Electronic address: drshow286@yahoo.com. 3. Department Of Anaesthesia And Intensive Care, Obafemi Awolowo University Teaching Hospitals Complex, Ileife, Osun State, Nigeria. Electronic address: tonieadenekan@yahoo.com. 4. Department Of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun State, Nigeria. Electronic address: sanya_adejuyigbe@yahoo.co.uk. 5. Department Of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun State, Nigeria. Electronic address: collinsadumah@yahoo.com. 6. Department Of Surgery, Obafemi Awolowo University Teaching Hospitals Complex, Ile - Ife, Osun State, Nigeria. Electronic address: aruaobasi@yahoo.com.
Abstract
BACKGROUND/ PURPOSE: The analysis of perioperative mortality as well as surgery- and anesthesia-related death in pediatric patients may serve as a potential tool to improve outcome. The aim of this study is to report the 24-h and 30-day overall, and surgery and anesthesia-related, mortality in a tertiary hospital. METHODS: This is a retrospective review of perioperative mortality in children ≤15years at a general pediatric surgery unit. All pediatric general surgery cases operated under general anesthesia between January 2007 and December 2016 were included in the study and data analyzed. RESULTS: A total of 4108 surgical procedures were performed in 4040 patients. The age was 1day to 15years with a median age of 2years. The all cause 24-h mortality was 34 per 10,000 procedures and the all cause 30-day mortality was 156 per 10,000 procedures. Septicemia was the most common cause of death. The determinants of mortality were neonatal age group (Adjusted Odd Ratio (AOR)=0.033, 95% CI=0.015-0.070, p=0.001), emergency surgery (AOR=90.91, 95% CI=27.78-333.33, p=0.001), higher ASA status (AOR=0.014, 95% CI=0.005-0.041, p=0.001) and multiple operative procedures (AOR=38.46, 95% CI=10.64-142.85, p=0.001). CONCLUSIONS: Neonatal age group, children with poorer ASA status, emergency and multiple surgeries were predictors of perioperative mortality. LEVEL OF EVIDENCE: Retrospective study.
BACKGROUND/ PURPOSE: The analysis of perioperative mortality as well as surgery- and anesthesia-related death in pediatric patients may serve as a potential tool to improve outcome. The aim of this study is to report the 24-h and 30-day overall, and surgery and anesthesia-related, mortality in a tertiary hospital. METHODS: This is a retrospective review of perioperative mortality in children ≤15years at a general pediatric surgery unit. All pediatric general surgery cases operated under general anesthesia between January 2007 and December 2016 were included in the study and data analyzed. RESULTS: A total of 4108 surgical procedures were performed in 4040 patients. The age was 1day to 15years with a median age of 2years. The all cause 24-h mortality was 34 per 10,000 procedures and the all cause 30-day mortality was 156 per 10,000 procedures. Septicemia was the most common cause of death. The determinants of mortality were neonatal age group (Adjusted Odd Ratio (AOR)=0.033, 95% CI=0.015-0.070, p=0.001), emergency surgery (AOR=90.91, 95% CI=27.78-333.33, p=0.001), higher ASA status (AOR=0.014, 95% CI=0.005-0.041, p=0.001) and multiple operative procedures (AOR=38.46, 95% CI=10.64-142.85, p=0.001). CONCLUSIONS: Neonatal age group, children with poorer ASA status, emergency and multiple surgeries were predictors of perioperative mortality. LEVEL OF EVIDENCE: Retrospective study.
Authors: Sarah Peiffer; Anna E Ssentongo; Laura Keeney; Forster Amponsah-Manu; Richard Yeboako; Richard Ofosu-Akromah; Temitope Ebenezer Arkorful; Eric Agyemang; Anthony Tsai; John Oh; Paddy Ssentongo Journal: BMC Surg Date: 2020-09-22 Impact factor: 2.102