Literature DB >> 2960612

Suppression of delayed-type hypersensitivity to histocompatibility antigens by ultraviolet radiation.

A Molendijk1, R J van Gurp, I G Donselaar, R Benner.   

Abstract

Delayed-type hypersensitivity (DTH) reactions to allogeneic histocompatibility antigens in mice could be systemically suppressed by a single exposure to UV-B irradiation. The extent of suppression reached its maximum 4 days after irradiation, gradually waned thereafter, and disappeared at Day 21. Re-exposure of these mice to UV-B after waning reinduced the state of suppression. The suppression could be transferred to naive mice by means of splenic T lymphocytes. The suppressor T (Ts) cells suppressed the proliferative activity in the lymph nodes draining the site of immunization, but not the activity of already activated DTH-reactive T cells. Phenotypical analysis of these Ts cells revealed that two subpopulations of T cells are involved: one with the Lyt-1+, 2- phenotype, the other with the Lyt-1-, 2+ phenotype.

Entities:  

Mesh：

Substances：

Year:  1987        PMID： 2960612      PMCID： PMC1453979     

Source DB:  PubMed          Journal:  Immunology        ISSN： 0019-2805            Impact factor:   7.397


  29 in total

1.  Tolerance and contact sensitivity to DNFB in mice. VI. Inhibition of afferent sensitivity by suppressor T cells in adoptive tolerance.

Authors:  J W Moorhead
Journal:  J Immunol       Date:  1976-09       Impact factor: 5.422

2.  Circulating suppressor factors in mice subjected to ultraviolet irradiation and contact sensitization.

Authors:  T G Harriott-Smith; W J Halliday
Journal:  Immunology       Date:  1986-02       Impact factor: 7.397

3.  T1 and T2 lymphocytes in primary and secondary delayed type hypersensitivity of mice. I. Contribution in the response to sheep red blood cells and to allogeneic spleen cells.

Authors:  T H van der Kwast; R Benner
Journal:  Cell Immunol       Date:  1978-08       Impact factor: 4.868

4.  Dose-response characteristics of immunologic unresponsiveness to UV-induced tumors produced by UV irradiation of mice.

Authors:  E C DeFabo; M L Kripke
Journal:  Photochem Photobiol       Date:  1979-09       Impact factor: 3.421

5.  Modification of immunological potential by ultraviolet radiation. II. Generation of suppressor cells in short-term UV-irradiated mice.

Authors:  C W Spellman; R A Daynes
Journal:  Transplantation       Date:  1977-08       Impact factor: 4.939

6.  Synergism of T lymphocyte subsets in the response to Mls-locus coded antigens during graft-versus-host reaction.

Authors:  H Bril; B D Molendijk-Lok; L M Hussaarts-Odijk; R Benner
Journal:  Cell Immunol       Date:  1984-02       Impact factor: 4.868

7.  Two phenotypically distinct T cells (Ly1+2- and Ly1-2+) are involved in ultraviolet-B light-induced suppression of the efferent DTH response to HSV-1 in vivo.

Authors:  S E Howie; M Norval; J Maingay; J A Ross
Journal:  Immunology       Date:  1986-08       Impact factor: 7.397

8.  Mechanism of systemic immune suppression by UV irradiation in vivo. II. The UV effects on number and morphology of epidermal Langerhans cells and the UV-induced suppression of contact hypersensitivity have different wavelength dependencies.

Authors:  F P Noonan; C Bucana; D N Sauder; E C De Fabo
Journal:  J Immunol       Date:  1984-05       Impact factor: 5.422

9.  Suppression of graft-versus-host reactivity in the mouse popliteal node by UVB radiation.

Authors:  W L Morison; R A Pike
Journal:  J Invest Dermatol       Date:  1985-06       Impact factor: 8.551

10.  Impairment of antigen-presenting cell function by ultraviolet radiation. II. Effect of in vitro ultraviolet irradiation on antigen-presenting cells.

Authors:  I J Fox; M S Sy; B Benacerraf; M I Greene
Journal:  Transplantation       Date:  1981-04       Impact factor: 4.939
View more
  3 in total

1.  Prostaglandin E2-prostaglandin E receptor subtype 4 (EP4) signaling mediates UV irradiation-induced systemic immunosuppression.

Authors:  Kitipong Soontrapa; Tetsuya Honda; Daiji Sakata; Chengcan Yao; Takako Hirata; Shohei Hori; Toshiyuki Matsuoka; Yoshihiro Kita; Takao Shimizu; Kenji Kabashima; Shuh Narumiya
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-01       Impact factor: 11.205

2.  Irradiation of murine donor spleen cells with ultraviolet "B" light eliminates graft-versus-host and host-versus-graft response in allogeneic recipient mice.

Authors:  S L Smith; J A Martinson; J Welter; J E Miripol
Journal:  In Vitro Cell Dev Biol Anim       Date:  1997-10       Impact factor: 2.416

3.  Integrative genetic analysis suggests that skin color modifies the genetic architecture of melanoma.

Authors:  Imge Hulur; Andrew D Skol; Eric R Gamazon; Nancy J Cox; Kenan Onel
Journal:  PLoS One       Date:  2017-10-03       Impact factor: 3.240
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.