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Literature DB >> 29605099

CRISPR/Cas13 as a Tool for RNA Interference.

Zahir Ali¹, Ahmed Mahas¹, Magdy Mahfouz².

Abstract

Almost all biological processes involve RNA, making it crucial to develop tools for manipulation of the transcriptome. The bacterial CRISPR/Cas13 system was recently rewired to facilitate RNA manipulation in eukaryotes, including plants. We discuss here the opportunities and limitations of using CRISPR/Cas13 in plants for various types of RNA manipulation.

Keywords: CRISPR/Cas13; RNA manipulation; transcriptome regulation; viral interference

Mesh：

Substances：
RNA, Plant
RNA, Viral
RNA

Year: 2018 PMID： 29605099 DOI： 10.1016/j.tplants.2018.03.003

Source DB: PubMed Journal: Trends Plant Sci ISSN： 1360-1385 Impact factor: 18.313

Keyword Cloud
Cited

15 in total

Review 1. General guidelines for CRISPR/Cas-based genome editing in plants.

Authors: Musa Kavas; Ceyhun Kayihan; Ufuk Demirel; Emre Aksoy; Kubilay Yildirim; Bayram Ali Yerlikaya; Irmak Çalik; İlkay Sevgen
Journal: Mol Biol Rep Date: 2022-09-15 Impact factor: 2.742

2. Engineering plant architecture via CRISPR/Cas9-mediated alteration of strigolactone biosynthesis.

Authors: Haroon Butt; Muhammad Jamil; Jian You Wang; Salim Al-Babili; Magdy Mahfouz
Journal: BMC Plant Biol Date: 2018-08-29 Impact factor: 4.215

3. Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis.

Authors: Rashid Aman; Ahmed Mahas; Haroon Butt; Fatimah Aljedaani; Magdy Mahfouz
Journal: Viruses Date: 2018-12-19 Impact factor: 5.048

4. DNA-Free Genome Editing: Past, Present and Future.

Authors: Janina Metje-Sprink; Jochen Menz; Dominik Modrzejewski; Thorben Sprink
Journal: Front Plant Sci Date: 2019-01-14 Impact factor: 5.753

Review 5. Human Long Noncoding RNA Interactome: Detection, Characterization and Function.

Authors: Marek Kazimierczyk; Marta K Kasprowicz; Marta E Kasprzyk; Jan Wrzesinski
Journal: Int J Mol Sci Date: 2020-02-04 Impact factor: 5.923

6. Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression.

Authors: Priscilla Ying Lei Tng; Leonela Carabajal Paladino; Sebald Alexander Nkosana Verkuijl; Jessica Purcell; Andres Merits; Philip Thomas Leftwich; Rennos Fragkoudis; Rob Noad; Luke Alphey
Journal: Commun Biol Date: 2020-07-31

CRISPR/Cas13 as a Tool for RNA Interference.

Review 1. General guidelines for CRISPR/Cas-based genome editing in plants.

2. Engineering plant architecture via CRISPR/Cas9-mediated alteration of strigolactone biosynthesis.

3. Engineering RNA Virus Interference via the CRISPR/Cas13 Machinery in Arabidopsis.

4. DNA-Free Genome Editing: Past, Present and Future.

Review 5. Human Long Noncoding RNA Interactome: Detection, Characterization and Function.

6. Cas13b-dependent and Cas13b-independent RNA knockdown of viral sequences in mosquito cells following guide RNA expression.

Review 7. Class 2 CRISPR/Cas: an expanding biotechnology toolbox for and beyond genome editing.

8. Programmable CRISPR interference for gene silencing using Cas13a in mosquitoes.

9. CRISPR-Cas13d mediates robust RNA virus interference in plants.

10. CRISPR/Cas13d-mediated efficient KDM5B mRNA knockdown in porcine somatic cells and parthenogenetic embryos.