Literature DB >> 29603270

Value of a novel 16-lead High-Definition ECG machine to detect conduction abnormalities in structural heart disease.

Guo-Liang Li1,2, Ardan M Saguner3, Deniz Akdis3, Guy Hugues Fontaine2,4.   

Abstract

BACKGROUND: Depolarization abnormalities are hardly detectable by standard 12-lead electrocardiogram (ECG) in some patients.
OBJECTIVE: To evaluate the value of the 16-lead High-Definition (HD)-ECG machine to record conduction abnormalities including Epsilon waves in patients with structural heart disease.
METHODS: Tracings with 12-lead ECG, 16-lead HD-ECG, and signal-averaged ECG were studied.
RESULTS: (1) Case of severe coronary artery disease (CAD): On 16-lead HD-ECG, a tiny intra-QRS signal was noted in lead III, a prolonged P wave in lead II, and fragmentation on top of lead aVL and lead aVF. Proper automatic measurement of the prolonged P wave measuring 190 ms was noted. Signal-averaging by 16-lead HD-ECG in lead III showed the intra-QRS fragmentation and P wave prolongation of 180 ms. (2) First patient with arrhythmogenic right ventricular dysplasia (ARVD): Standard 12-lead ECG indicated Epsilon waves in lead III, V2, V3, and inverted T waves in V1-V3. 16-lead HD-ECG indicated QRS prolongation in lead II, III, aVL, aVF, V2, V3 as opposed to V6, and low amplitudes of QRS complexes in V4R and V3R as a new possible sign of ARVD. Notches in lead V2, widening of QRS complexes in all precordial leads, but shorter QRS in V8-V9 are also considered as a potential new diagnostic sign of ARVD. (3) Second ARVD patient: Notches at the end of the QRS in lead III and a negative initial deflection of the QRS in V1 and V2 were detected by standard 12-lead ECG. On 16-lead HD-ECG, a more pronounced QRS fragmentation was visible.
CONCLUSION: 16-lead HD-ECG in both CAD and ARVD seems to be more sensitive than 12-lead ECG to record electrocardiographic abnormalities.
© 2018 Wiley Periodicals, Inc.

Entities:  

Keywords:  ECG; Epsilon waves; Fontaine Lead System; arrhythmic right ventricular dysplasia; coronary artery disease

Mesh:

Year:  2018        PMID: 29603270     DOI: 10.1111/pace.13338

Source DB:  PubMed          Journal:  Pacing Clin Electrophysiol        ISSN: 0147-8389            Impact factor:   1.976


  2 in total

Review 1.  Epsilon waves: Milestones in the discovery and progress.

Authors:  Guo-Liang Li; Ardan M Saguner; Guy Hugues Fontaine; Robert Frank
Journal:  Ann Noninvasive Electrocardiol       Date:  2018-07-05       Impact factor: 1.468

Review 2.  Epsilon Waves as an Extreme Form of Depolarization Delay: Focusing on the Arrhythmogenic Right Ventricular Cardiomyopathy/Dysplasia.

Authors:  Pyotr G Platonov; Anneli Svensson
Journal:  Curr Cardiol Rev       Date:  2021
  2 in total

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