Literature DB >> 29601207

Nonsurgical Treatments of Patellar Tendinopathy: Multiple Injections of Platelet-Rich Plasma Are a Suitable Option: A Systematic Review and Meta-analysis.

Luca Andriolo1, Sante Alessandro Altamura1, Davide Reale1, Christian Candrian2, Stefano Zaffagnini1, Giuseppe Filardo3.   

Abstract

BACKGROUND: Patellar tendinopathy is a condition characterized by anterior knee activity-related pain. It has a high incidence among athletes engaged in jumping sports and may become a chronic condition. Nonoperative management is the first choice in these patients, and several nonsurgical treatment options have been proposed. Nonetheless, clear indications on the most effective approach to address patellar tendinopathy are still lacking.
PURPOSE: To analyze the evidence on nonoperative options to treat chronic patellar tendinopathy through a systematic review of the literature and to perform a meta-analysis to identify the most effective nonsurgical option. STUDY
DESIGN: Systematic review and meta-analysis.
METHODS: The search was conducted with the PubMed and Cochrane databases on January 4, 2017. All clinical English-language reports of any level of evidence on nonsurgical treatment of patellar tendinopathy were included. The quality of each article was assessed by use of the Coleman score. A meta-analysis was performed on all articles reporting the Victorian Institute of Sport Assessment scale for patellar tendinopathy to evaluate the results of the most described treatments.
RESULTS: A total of 70 studies involving 2530 patients were included in the qualitative data synthesis. The Coleman score showed an overall poor study quality. The most described treatment groups that could be included in the meta-analysis were reported in 22 studies on eccentric exercise, extracorporeal shockwave therapy (ESWT), and platelet-rich plasma (PRP). Single and multiple PRP injections were evaluated separately. Eccentric exercise therapies obtained the best results ( P < .05) at short-term (<6 months, mean 2.7 ± 0.7 months). However, multiple injections of PRP obtained the best results ( P < .05), followed by ESWT and eccentric exercise, at long-term follow-up (≥6 months, mean 15.1 ± 11.3 months).
CONCLUSION: The literature documents several nonsurgical approaches for the treatment of chronic patellar tendinopathy with important limitations in terms of study quality. The available evidence showed an overall positive outcome, but some differences have been highlighted. Eccentric exercises may seem the strategy of choice in the short-term, but multiple PRP injections may offer more satisfactory results at long-term follow-up and can be therefore considered a suitable option for the treatment of patellar tendinopathy.

Entities:  

Keywords:  ESWT; PRP; eccentric exercise; jumper’s knee; nonoperative treatment; patellar tendinopathy

Mesh:

Year:  2018        PMID: 29601207     DOI: 10.1177/0363546518759674

Source DB:  PubMed          Journal:  Am J Sports Med        ISSN: 0363-5465            Impact factor:   6.202


  17 in total

1.  Platelet-rich plasma for sports-related muscle, tendon and ligament injuries: an umbrella review.

Authors:  Mario Cruciani; Massimo Franchini; Carlo Mengoli; Giuseppe Marano; Ilaria Pati; Francesca Masiello; Samantha Profili; Eva Veropalumbo; Simonetta Pupella; Stefania Vaglio; Giancarlo M Liumbruno
Journal:  Blood Transfus       Date:  2019-12-11       Impact factor: 3.443

2.  2019-2020 NFL and NFL Physician Society Orthobiologics Consensus Statement.

Authors:  Scott A Rodeo; Asheesh Bedi
Journal:  Sports Health       Date:  2019-11-18       Impact factor: 3.843

3.  The use of platelet-rich plasma in management of musculoskeletal pain: a narrative review.

Authors:  Aung Chan Thu
Journal:  J Yeungnam Med Sci       Date:  2022-06-08

4.  Platelet-Rich Plasma for Sport-Active Patients with Knee Osteoarthritis: Limited Return to Sport.

Authors:  Sante Alessandro Altamura; Alessandro Di Martino; Luca Andriolo; Angelo Boffa; Stefano Zaffagnini; Annarita Cenacchi; Maria Stella Zagarella; Giuseppe Filardo
Journal:  Biomed Res Int       Date:  2020-01-31       Impact factor: 3.411

Review 5.  Platelet-Rich Plasma: Review of Current Literature on its Use for Tendon and Ligament Pathology.

Authors:  Cameron Kia; Joshua Baldino; Ryan Bell; Alim Ramji; Colin Uyeki; Augustus Mazzocca
Journal:  Curr Rev Musculoskelet Med       Date:  2018-12

6.  IN-SEASON REHABILITATION PROGRAM USING BLOOD FLOW RESTRICTION THERAPY FOR TWO DECATHLETES WITH PATELLAR TENDINOPATHY: A CASE REPORT.

Authors:  Tyler Cuddeford; Jason Brumitt
Journal:  Int J Sports Phys Ther       Date:  2020-12

Review 7.  Intra-articular platelet-rich plasma injection for knee osteoarthritis: a summary of meta-analyses.

Authors:  Pu Chen; Liuwei Huang; Yufeng Ma; Dong Zhang; Xiaozhe Zhang; Jun Zhou; Anmin Ruan; Qingfu Wang
Journal:  J Orthop Surg Res       Date:  2019-11-27       Impact factor: 2.359

8.  Response to: Comment on "Responders to Platelet-Rich Plasma in Osteoarthritis: A Technical Analysis".

Authors:  Christophe Milants; Olivier Bruyère; Jean-François Kaux
Journal:  Biomed Res Int       Date:  2018-09-06       Impact factor: 3.411

9.  Comparative study of treatment interventions for patellar tendinopathy: a protocol for a randomised controlled trial.

Authors:  Maria Pilar López-Royo; Eva Maria Gómez-Trullén; Maria Ortiz-Lucas; Rita Maria Galán-Díaz; Ana Vanessa Bataller-Cervero; Zaid Al-Boloushi; Yasmina Hamam-Alcober; Pablo Herrero
Journal:  BMJ Open       Date:  2020-02-16       Impact factor: 2.692

10.  Surgical Technique for Chronic Proximal Patellar Tendinopathy (Jumper's Knee).

Authors:  Alfredo Marques Villardi; João Gabriel de Cerqueira Campos Villardi; Rafael Erthal de Paula; Tiago Carminatti; Raphael Serra Cruz
Journal:  Arthrosc Tech       Date:  2019-11-13
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