Literature DB >> 29600123

Association Between Baseline Blood Pressures, Heart Rates, and Vasovagal Syncope in Children and Adolescents.

Himanshu Adlakha1, Ruchi Gupta2, Romana Hassan3, Jeffrey H Kern4.   

Abstract

BACKGROUND: Vasovagal syncope is the most common cause of syncope in children and adults, accounting for 50-66% of unexplained syncope. There are no studies establishing the relationship between syncope, baseline heart rate, and blood pressure.
OBJECTIVE: To identify a possible association between baseline blood pressure and heart rate with syncope. DESIGN/
METHODS: We conducted a questionnaire-based chart review study. A questionnaire was distributed to the guardian of children between eight and 18 years of age who attended the Pediatric Ambulatory Care Clinic at Flushing Hospital Medical Center. Based on the responses in the questionnaire, subjects were classified either as cases (positive for syncope) or controls (negative for syncope). Children and adolescents with neurological, cardiac, or any medical condition that can cause syncopal episodes were excluded from the study. Data collected from the questionnaire included age, gender, ethnicity, medical history, family history of syncope, and the amount of salt used in food. Anthropometric and vital signs for the current visit (height, weight, BMI, blood pressure, and heart rate) and vital signs from two previous visits were collected from electronic medical records. The data was analyzed using t-test and chi-square test with Microsoft Excel software (Microsoft Office Standard, v. 14, Microsoft; 2010); p<0.05 was considered significant.
RESULTS: A total of 197 subjects were included in this study. There were 18 cases and 179 controls. Of the cases, (4/18) 22.2% were more likely to have a systolic blood pressure lower than the 10th percentile for their gender, age, and height as compared with controls (7/179) 3.9%, p = 0.003. The subjects with a history of syncope were more likely to add salt to their food (p = 0.004). There were no significant differences between cases and controls for age, gender, ethnicity between cases and controls for systolic blood pressure. No significant difference was observed between the heart rates of cases and controls.
CONCLUSIONS: Children and adolescents with syncope were more likely to have a systolic blood pressure lower than the 10th percentile, and there was no difference in the baseline heart rate. In addition, children with syncope were more likely to add salt to their food.

Entities:  

Keywords:  benign syncope; fainting; low baseline blood pressure; salt intake; vasovagal syncope

Year:  2018        PMID: 29600123      PMCID: PMC5873830          DOI: 10.7759/cureus.2119

Source DB:  PubMed          Journal:  Cureus        ISSN: 2168-8184


  14 in total

1.  Syncope. Physiological considerations and an analysis of the clinical characteristics in 510 patients.

Authors:  H H WAYNE
Journal:  Am J Med       Date:  1961-03       Impact factor: 4.965

2.  Guidelines for the diagnosis and management of syncope (version 2009).

Authors:  Angel Moya; Richard Sutton; Fabrizio Ammirati; Jean-Jacques Blanc; Michele Brignole; Johannes B Dahm; Jean-Claude Deharo; Jacek Gajek; Knut Gjesdal; Andrew Krahn; Martial Massin; Mauro Pepi; Thomas Pezawas; Ricardo Ruiz Granell; Francois Sarasin; Andrea Ungar; J Gert van Dijk; Edmond P Walma; Wouter Wieling
Journal:  Eur Heart J       Date:  2009-08-27       Impact factor: 29.983

3.  Diagnostic value of history in patients with syncope with or without heart disease.

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Journal:  Circulation       Date:  2001-09-11       Impact factor: 29.690

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Authors:  Margaret J Strieper
Journal:  Semin Pediatr Neurol       Date:  2005-03       Impact factor: 1.636

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Authors:  C J Mathias; K Deguchi; I Schatz
Journal:  Lancet       Date:  2001-02-03       Impact factor: 79.321

7.  Exercise-related syncope in young competitive athletes without evidence of structural heart disease. Clinical presentation and long-term outcome.

Authors:  F Colivicchi; F Ammirati; A Biffi; L Verdile; A Pelliccia; M Santini
Journal:  Eur Heart J       Date:  2002-07       Impact factor: 29.983

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Authors:  M Igarashi; R M Boehm; W N May; J H Bornhofen
Journal:  Brain Dev       Date:  1988       Impact factor: 1.961

9.  Self-reported symptom burden; outcome in 418 patients from the Newcastle Vasovagal (Neurocardiogenic) cohort.

Authors:  R Ross; S Parry; M Norton; J L Newton
Journal:  QJM       Date:  2008-01-09

10.  Syncope associated with exercise, a manifestation of neurally mediated syncope.

Authors:  S Sakaguchi; J J Shultz; S C Remole; S W Adler; K G Lurie; D G Benditt
Journal:  Am J Cardiol       Date:  1995-03-01       Impact factor: 2.778

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  1 in total

1.  Predictor of Syncopal Recurrence in Children With Vasovagal Syncope Treated With Metoprolol.

Authors:  Chunyan Tao; Bowen Xu; Ying Liao; Xueying Li; Hongfang Jin; Junbao Du
Journal:  Front Pediatr       Date:  2022-04-08       Impact factor: 3.569

  1 in total

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