Literature DB >> 29599895

Corrigendum to "Cytoprotective and Cytotoxic Effects of Rice Bran Extracts in Rat H9c2(2-1) Cardiomyocytes".

Xian Wen Tan1,2, Mrinal Bhave3, Alan Yean Yip Fong4,5, Eiji Matsuura6,7, Kazuko Kobayashi6,7, Lian Hua Shen6,7, Siaw San Hwang1,2.   

Abstract

[This corrects the article DOI: 10.1155/2016/6943053.].

Entities:  

Year:  2018        PMID: 29599895      PMCID: PMC5828281          DOI: 10.1155/2018/3136860

Source DB:  PubMed          Journal:  Oxid Med Cell Longev        ISSN: 1942-0994            Impact factor:   6.543


In the article titled “Cytoprotective and Cytotoxic Effects of Rice Bran Extracts in Rat H9c2(2-1) Cardiomyocytes” [1], errors in statistical analyses for inhibitory concentration (IC50) have resulted in incorrect tabulations of data for both Tables 2 and 4. The corrected versions of both tables are as below.
Table 2

The relative inhibitory concentration (IC50) of RBE of BJLN and MR219. Data presented as mean ± standard deviation of three technical replicates (n = 3).

BJLNMR219
Log (dose)(μg/mL)Dose(μg/mL)Log (dose)(μg/mL)Dose(μg/mL)
Day 1(24 hours)1.808 ± 0.01164.271.980 ± 0.01395.56
Day 2(48 hours)1.775 ± 0.00259.572.047 ± 0.026111.40
Day 3(72 hours)1.800 ± 0.00463.102.033 ± 0.029108.00
Table 4

Average IC50 of H2O2 for H9c2(2-1) cells. The IC50 value was determined from respective cell viability curves ( Figure 5) via GraphPad Prism (GraphPad Software Inc., USA). Data represent mean ± standard deviation of 3 (n = 3). ∗ denotes significantly different from negative control treated with media + 1% EtOH at P ≤ 0.05. Graphical representations of data were depicted in Figure 5.

Average IC50 of H2O2 (μM)
Log [H2O2]H2O2
Control sample
 Negative control (media + 1% EtOH)2.433 ± 0.040271.00
RBE
 BJLN (25 μg/mL)2.776 ± 0.028 597.20
 BJLN (50 μg/mL)1.954 ± 0.033 89.95
 MR219 (50 μg/mL)2.561 ± 0.035 364.20
 MR219 (100 μg/mL)2.158 ± 0.032 143.90
Accordingly, in the “Results” (Section 3.1), the text reading “Based on the results ( hours of incubation time.” should be corrected to “Based on the results (.”, and “Based on the results, the IC” should be corrected to “Based on the results, the IC” In addition, in the “Results” (Section 3.3), the text reading “The positive effects were more distinctive with lower concentrations of RBE (BJLN: 25 μg/mL; MR219: 50 μg/mL) with observable increments in IC versus 1.4% (in approximation) when compared to negative control (316.23 μM).” should be replaced with “The positive effects were more distinctive with lower concentrations of RBE (BJLN: 25 μg/mL; MR219: 50 μg/mL) with observable increments in IC versus 1.4-fold (in approximation) when compared to negative control (271.00 μM).”, and the text reading “Significant decrements in the IC” should be replaced with “Significant decrements in the IC.” An incorrect version of Figure 3 with missing graphical elements was published. The corrected version of Figure 3 with the inclusion of graphical elements is as shown below.
Figure 3

Total contents of selected bioactive compounds in the RBE. Different letters on a bar represent significant differences at P ≤ 0.05 (Tukey's test).

Accordingly, Figure 5(b) presented in the original manuscript was also the incorrect version. The fourth datum point for MR219 (50 μg/mL) (grey dotted line) was incorrectly plotted. The correct version of the figure is as shown below with the corrected fourth datum point for MR219 (50 μg/mL) (grey dotted line).
Figure 5

Effects of H2O2 inductions on cell viabilities of H9c2(2-1) cardiomyocytes pretreated with different concentrations of (a) BJLN RBE (25 μg/mL and 50 μg/mL) and (b) MR219 RBE (50 μg/mL and 100 μg/mL).

  1 in total

1.  Cytoprotective and Cytotoxic Effects of Rice Bran Extracts in Rat H9c2(2-1) Cardiomyocytes.

Authors:  Xian Wen Tan; Mrinal Bhave; Alan Yean Yip Fong; Eiji Matsuura; Kazuko Kobayashi; Lian Hua Shen; Siaw San Hwang
Journal:  Oxid Med Cell Longev       Date:  2016-04-27       Impact factor: 6.543

  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.